Adjuvant physiochemistry and advanced nanotechnology for vaccine development
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …
Challenges in developing personalized neoantigen cancer vaccines
PD Katsikis, KJ Ishii, C Schliehe - Nature Reviews Immunology, 2024 - nature.com
The recent success of cancer immunotherapies has highlighted the benefit of harnessing the
immune system for cancer treatment. Vaccines have a long history of promoting immunity to …
immune system for cancer treatment. Vaccines have a long history of promoting immunity to …
Deciphering triterpenoid saponin biosynthesis by leveraging transcriptome response to methyl jasmonate elicitation in Saponaria vaccaria
Methyl jasmonate (MeJA) is a known elicitor of plant specialized metabolism, including
triterpenoid saponins. Saponaria vaccaria is an annual herb used in traditional Chinese …
triterpenoid saponins. Saponaria vaccaria is an annual herb used in traditional Chinese …
Harnessing engineered immune cells and bacteria as drug carriers for cancer immunotherapy
Immunotherapy continues to be in the spotlight of oncology therapy research in the past few
years and has been proven to be a promising option to modulate one's innate and adaptive …
years and has been proven to be a promising option to modulate one's innate and adaptive …
[HTML][HTML] Recent advances and clinical translation of liposomal delivery systems in cancer therapy
J Chen, S Hu, M Sun, J Shi, H Zhang, H Yu… - European Journal of …, 2024 - Elsevier
The limitations of conventional cancer treatment are driving the emergence and
development of nanomedicines. Research in liposomal nanomedicine for cancer therapy is …
development of nanomedicines. Research in liposomal nanomedicine for cancer therapy is …
Metal-based nano-vaccines for cancer immunotherapy
J Li, H Ren, Y Zhang - Coordination Chemistry Reviews, 2022 - Elsevier
Cancer vaccination is an effective way to prevent or cure cancers by inducing strong cellular
and humoral immunity with the aid of delivery carriers or adjuvants. Increasing new delivery …
and humoral immunity with the aid of delivery carriers or adjuvants. Increasing new delivery …
Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice
The COVID-19 pandemic has spurred interest in potent and thermostable SARS-CoV-2
vaccines. Here, we assess low-dose immunization with lyophilized nanoparticles decorated …
vaccines. Here, we assess low-dose immunization with lyophilized nanoparticles decorated …
Nanovaccines for cancer immunotherapy: current knowledge and future perspectives
Y Wu, Z Zhang, Y Wei, Z Qian, X Wei - Chinese Chemical Letters, 2023 - Elsevier
Cancer immunotherapy harnesses the immune system to attack tumors and has received
extensive attention in recent years. Cancer vaccines as an important branch of …
extensive attention in recent years. Cancer vaccines as an important branch of …
Understanding structure–function relationships of nanoadjuvants for enhanced cancer vaccine efficacy
J Tan, B Ding, B Teng, P Ma… - Advanced Functional …, 2022 - Wiley Online Library
Adjuvant, as an important part of vaccines, can observably enhance the magnitude, breadth
and durability of immune responses. Nanoadjuvants, as novel vaccine adjuvants, have …
and durability of immune responses. Nanoadjuvants, as novel vaccine adjuvants, have …
Vaccine approaches for antigen capture by liposomes
Introduction Liposomes have been used as carriers for vaccine adjuvants and antigens due
to their inherent biocompatibility and versatility as delivery vehicles. Two vial admixture of …
to their inherent biocompatibility and versatility as delivery vehicles. Two vial admixture of …