Several molecular mechanisms are involved in the regulation of skeletal muscle function.
Among them, mitochondrial activity can be identified. The mitochondria is an important and …

Lipid metabolism is an important and complex biochemical process involved in the storage
of energy and maintenance of normal biological functions. Leucine, a branched amino acid …

Mitochondrial diseases are a heterogeneous group of monogenic disorders that result from
impaired oxidative phosphorylation (OXPHOS). As neuromuscular tissues are highly energy …

Obesity-induced skeletal muscle (SKM) inflexibility is closely linked to mitochondrial
dysfunction. The present study aimed to evaluate the effects of melatonin on the red vastus …

Mitochondrial biology has become an area of intense research owing to the unique
physiology of the organelle and its role in several types of cancers and other disorders. It …

The aim of this review is to summarize and discuss recent findings and new insights in the
etiology and phenotype of metabolic myopathies. The review relies on a systematic literature …

Neuromuscular diseases (NMDs) are dysfunctions that involve skeletal muscle and cause
incorrect communication between the nerves and muscles. The specific causes of NMDs are …

Mitochondrial disorders are often difficult to diagnose because of diverse clinical
phenotypes. FGF-21 and GDF-15 are metabolic hormones and promising biomarkers for the …

Muscle diseases display mitochondrial dysfunction and oxidative damage. Our previous
study in a cardiotoxin model of myodegeneration correlated muscle damage with …

Abstract Analysis of human muscle diseases highlights the role of mitochondrial dysfunction
in the skeletal muscle. Our previous work revealed that diverse upstream events correlated …