Joint single-cell genetic and transcriptomic analysis reveal pre-malignant SCP-like subclones in human neuroblastoma
Background Neuroblastoma (NB) is a heterogeneous embryonal malignancy and the
deadliest tumor of infancy. It is a complex disease that can result in diverse clinical …
deadliest tumor of infancy. It is a complex disease that can result in diverse clinical …
Pediatric Tumors as Disorders of Development: The Case for In Vitro Modeling Based on Human Stem Cells
CD Clairmont, JJ Gell, CC Lau - Cancer Control, 2024 - journals.sagepub.com
Despite improvements in patient outcomes, pediatric cancer remains a leading cause of non-
accidental death in children. Recent genetic analysis of patients with pediatric cancers …
accidental death in children. Recent genetic analysis of patients with pediatric cancers …
[HTML][HTML] Synaptic vesicle protein 2-targeted doxorubicin-loaded liposome for effective neuroblastoma therapy
Y Liu, D Zhang, M Kong, Y Wang, H Mei, C Shan… - Biomedicine & …, 2024 - Elsevier
Neuroblastoma, a pediatric cancer originating from neural crest tissues of the sympathetic
nervous system, poses significant treatment challenges due to its molecular diversity and …
nervous system, poses significant treatment challenges due to its molecular diversity and …
METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma
Neuroblastoma (NB) is the most common extracranial childhood cancer, caused by the
improper differentiation of developing trunk neural crest cells (tNCC) in the sympathetic …
improper differentiation of developing trunk neural crest cells (tNCC) in the sympathetic …
A developmental cell atlas of the human thyroid gland
The primary function of the thyroid gland is the synthesis and release of thyroid hormones,
which are essential for health from embryogenesis to adulthood. Thyroid disorders occur …
which are essential for health from embryogenesis to adulthood. Thyroid disorders occur …
Comprehensive Enumeration of Cancer Stem-like Cell Heterogeneity Using Deep Neural Network
Cancer stem cells (CSCs), a distinct subpopulation within tumors, are pivotal in driving
treatment resistance and tumor recurrence, posing substantial challenges to conventional …
treatment resistance and tumor recurrence, posing substantial challenges to conventional …
METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma
S Turner - 2024 - repository.cam.ac.uk
Neuroblastoma (NB) is the most common extracranial childhood cancer, caused by the
improper differentiation of developing trunk neural crest cells (tNCC) in the sympathetic …
improper differentiation of developing trunk neural crest cells (tNCC) in the sympathetic …