In this review, we provide a detailed overview of studies on the elusive sex determination
(SD) and gonad differentiation mechanisms of zebrafish (Danio rerio). We show that the data …

Zebrafish sex determination, gonad differentiation and reproduction are far from being fully
understood. Although the mode of sex determination is still being disputed, most …

Inconsistent activity limits the use of CRISPR-Cas9 in zebrafish. We show supernumerary
guanine nucleotides at the 5′ ends of single guide RNAs (sgRNAs) account for diminished …

Zebrafish are an established research organism that has made many contributions to our
understanding of vertebrate tissue and organ development, yet there are still significant …

Although the zebrafish is a major model organism, how they determine sex is not well
understood. In domesticated zebrafish, sex determination appears to be polygenic, being …

A surprising diversity of mechanisms controls sex determination of vertebrate organisms,
even among closely related species. Both genetic and temperature-dependent systems of …

The aim of this study was to investigate the effects of progestins on the sex differentiation of
zebrafish by measuring the sex ratio and transcriptions of genes related to sex differentiation …

Development of the germline requires the specification and survival of primordial germ cells
(PGCs) in the embryo as well as the maintenance of gamete production during the …

Background The aim of this study was to identify differentially expressed ovarian genes
during primary and early secondary oocyte growth in coho salmon, a semelparous teleost …

In zebrafish, primordial germ cells (PGCs) are determined by a specialized maternal
cytoplasm, the germ plasm, which forms at the distal ends of the cleavage furrows in 4-cell …