Structural and functional aspects of P-glycoprotein and its inhibitors
Abstract P-glycoprotein (P-gp) is a member of ATP-binding cassette (ABC) superfamily
which extrudes chemotherapeutic agents out of the cell. Suppression of this efflux activity …
which extrudes chemotherapeutic agents out of the cell. Suppression of this efflux activity …
[HTML][HTML] Recent advances in access to overcome cancer drug resistance by nanocarrier drug delivery system
X Sun, P Zhao, J Lin, K Chen, J Shen - Cancer Drug Resistance, 2023 - ncbi.nlm.nih.gov
Cancer is currently one of the most intractable diseases causing human death. Although the
prognosis of tumor patients has been improved to a certain extent through various modern …
prognosis of tumor patients has been improved to a certain extent through various modern …
Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancer
S Mohana, M Ganesan, B Agilan, R Karthikeyan… - Molecular …, 2016 - pubs.rsc.org
P-Glycoprotein (P-gp) serves as a therapeutic target for the development of inhibitors to
overcome multidrug resistance in cancer cells. Although various screening procedures have …
overcome multidrug resistance in cancer cells. Although various screening procedures have …
[HTML][HTML] In vitro and in silico studies of salicylic acid on systemic induced resistance against bacterial leaf blight disease and enhancement of crop yield
W Thepbandit, NK Papathoti, JR Daddam… - Journal of Integrative …, 2023 - Elsevier
Salicylic acid (SA) is an effective elicitor to promote plant defenses and growth. This study
aimed to investigate rice (Oryza sativa L.) cv. Khao Dawk Mali 105 treated with salicylic acid …
aimed to investigate rice (Oryza sativa L.) cv. Khao Dawk Mali 105 treated with salicylic acid …
Emodin reverses leukemia multidrug resistance by competitive inhibition and downregulation of P-glycoprotein
H Min, M Niu, W Zhang, J Yan, J Li, X Tan, B Li, M Su… - PloS one, 2017 - journals.plos.org
Development of multidrug resistance (MDR) is a continuous clinical challenge partially due
to the overexpression of P-glycoprotein (P-gp) for chronic myelogenous leukemia (CML) …
to the overexpression of P-glycoprotein (P-gp) for chronic myelogenous leukemia (CML) …
Designing, docking and molecular dynamics simulation studies of novel cloperastine analogues as anti-allergic agents: Homology modeling and active site prediction …
The present study predicts a three-dimensional model for the histamine H1 receptor and the
design of antihistamine inhibitors using cloperastine as the core molecule by docking …
design of antihistamine inhibitors using cloperastine as the core molecule by docking …
Identification of Salicylic Acid Mechanism against Leaf Blight Disease in Oryza sativa by SR-FTIR Microspectroscopic and Docking Studies
The present study was to investigate the application and mechanism of salicylic acid (SA) as
SA-Ricemate for the control of leaf blight disease using a Synchrotron Radiation-based …
SA-Ricemate for the control of leaf blight disease using a Synchrotron Radiation-based …
Effects of environmental heat load on endocannabinoid system components in adipose tissue of high yielding dairy cows
Simple Summary We hypothesized that environmental heat load (HL) may affect the
endocannabinoid system (ECS), a central regulator of metabolism and the stress response …
endocannabinoid system (ECS), a central regulator of metabolism and the stress response …
Antioxidant resveratrol increases lipolytic and reduces lipogenic gene expression under in vitro heat stress conditions in dedifferentiated adipocyte-derived progeny …
Heat stress (HS) induces oxidative stress by increasing reactive oxygen species (ROS), and
the polyphenol resveratrol (RSV) has been shown to have antioxidant properties by …
the polyphenol resveratrol (RSV) has been shown to have antioxidant properties by …
In Silico studies on anti-stress compounds of ethanolic root extract of Hemidesmus indicus L.
JR Daddam, B Sreenivasulu… - Current …, 2020 - ingentaconnect.com
Background: Alternative medicine is available for those diseases which cannot be treated by
conventional medicine. Ayurveda and herbal medicines are important alternative methods in …
conventional medicine. Ayurveda and herbal medicines are important alternative methods in …