Chronic spontaneous urticaria: focus on pathophysiology to unlock treatment advances

A Kaplan, M Lebwohl, AM Giménez‐Arnau, M Hide… - Allergy, 2023 - Wiley Online Library
Chronic spontaneous urticaria (CSU) is a debilitating skin disease characterized by
intensely itchy wheals, angioedema, or both. Symptoms recur spontaneously, on a near …

Biologics for the use in chronic spontaneous urticaria: when and which

M Maurer, DA Khan, DEA Komi, AP Kaplan - The Journal of Allergy and …, 2021 - Elsevier
Guidelines for the treatment of chronic spontaneous urticaria (CSU) recommend the use of
the IgE-targeted biologic omalizumab in patients with antihistamine-refractory disease. The …

[HTML][HTML] Ligelizumab for chronic spontaneous urticaria

M Maurer, AM Giménez-Arnau… - … England Journal of …, 2019 - Mass Medical Soc
Background In the majority of patients with chronic spontaneous urticaria, most currently
available therapies do not result in complete symptom control. Ligelizumab is a next …

Omalizumab updosing in chronic spontaneous urticaria: an overview of real-world evidence

M Metz, Z Vadasz, E Kocatürk… - Clinical reviews in allergy …, 2020 - Springer
Chronic spontaneous urticaria (CSU) is defined as the spontaneous development of itchy
hives and/or angioedema due to known or unknown causes that last for at least 6 weeks. At …

How to treat patients with chronic spontaneous urticaria with omalizumab: questions and answers

M Türk, L Carneiro-Leão, P Kolkhir, H Bonnekoh… - The Journal of Allergy …, 2020 - Elsevier
Omalizumab is an effective treatment for patients with chronic spontaneous urticaria (CSU).
In routine clinical practice, physicians often face complex cases of CSU and need to decide …

Chronic rhinosinusitis with nasal polyps: targeting IgE with anti-IgE omalizumab therapy

HH Kariyawasam, LK James - Drug design, development and …, 2020 - Taylor & Francis
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex, clinically heterogeneous
and persistent inflammatory disorder of the upper airway. Detailed mechanistic insights into …

Update on omalizumab for urticaria: what's new in the literature from mechanisms to clinic

DES Larenas-Linnemann, CAS Parisi, C Ritchie… - Current Allergy and …, 2018 - Springer
Abstract Purpose of Review Since omalizumab has been approved for urticaria, numerous
randomized and real-life observational trials have been published. We reviewed the period …

What's new in the treatment of urticaria and angioedema

DA Khan, E Kocatürk, A Bauer… - The Journal of Allergy and …, 2021 - Elsevier
Chronic urticaria and angioedema are diseases often managed by Allergy and Immunology
specialists. Recent international guidelines have outlined a stepwise approach to …

The real-life effectiveness and safety of omalizumab updosing in patients with chronic spontaneous urticaria

A Salman, E Comert - Journal of Cutaneous Medicine and …, 2019 - journals.sagepub.com
Background: Omalizumab is a third-line treatment for chronic spontaneous urticaria (CSU).
Studies investigating the use of higher doses of omalizumab in patients unresponsive to …

Factors related to omalizumab drug survival and treatment responses in chronic urticaria

E Hasal, E Bulbul Baskan, S Yazici… - International archives of …, 2022 - karger.com
Introduction: This study aimed to evaluate factors affecting drug survival and treatment
response in patients with chronic urticaria treated with omalizumab in clinical practice …