Examining variation in the measurement of multimorbidity in research: a systematic review of 566 studies

ISS Ho, A Azcoaga-Lorenzo, A Akbari… - The Lancet Public …, 2021 - thelancet.com
Background A systematic understanding of how multimorbidity has been constructed and
measured is unavailable. This review aimed to examine the definition and measurement of …

Frailty and multimorbidity: a systematic review and meta-analysis

DL Vetrano, K Palmer, A Marengoni… - The Journals of …, 2019 - academic.oup.com
Background Multimorbidity and frailty are complex syndromes characteristics of aging. We
reviewed the literature and provided pooled estimations of any evidence regarding (a) the …

Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493 737 UK Biobank participants

P Hanlon, BI Nicholl, BD Jani, D Lee… - The Lancet Public …, 2018 - thelancet.com
Background Frailty is associated with older age and multimorbidity (two or more long-term
conditions); however, little is known about its prevalence or effects on mortality in younger …

The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis

J Muscedere, B Waters, A Varambally… - Intensive care …, 2017 - Springer
Purpose Functional status and chronic health status are important baseline characteristics of
critically ill patients. The assessment of frailty on admission to the intensive care unit (ICU) …

The Asia-Pacific clinical practice guidelines for the management of frailty

E Dent, C Lien, WS Lim, WC Wong, CH Wong… - Journal of the American …, 2017 - Elsevier
Abstract Objective To develop Clinical Practice Guidelines for the screening, assessment
and management of the geriatric condition of frailty. Methods An adapted Grading of …

Multimorbidity and mortality in older adults: a systematic review and meta-analysis

BP Nunes, TR Flores, GI Mielke, E Thume… - Archives of gerontology …, 2016 - Elsevier
Objective To review literature and provide a pooled effect for the association between
multimorbidity and mortality in older adults. Methods A systematic review was performed of …

[HTML][HTML] Cognitive frailty: rational and definition from an (IANA/IAGG) international consensus group

E Kelaiditi, M Cesari, M Canevelli, GA Van Kan… - The Journal of nutrition …, 2013 - Elsevier
The frailty syndrome has recently attracted attention of the scientific community and public
health organizations as precursor and contributor of age-related conditions (particularly …

Oral frailty indicators to target major adverse health-related outcomes in older age: a systematic review

V Dibello, F Lobbezoo, M Lozupone, R Sardone… - Geroscience, 2023 - Springer
A well-preserved oral function is key to accomplishing essential daily tasks. However, in
geriatric medicine and gerodontology, as age-related physiological decline disrupts several …

Modifications to the frailty phenotype criteria: Systematic review of the current literature and investigation of 262 frailty phenotypes in the Survey of Health, Ageing, and …

O Theou, L Cann, J Blodgett, LMK Wallace… - Ageing research …, 2015 - Elsevier
We conducted a systematic review to determine variability in how the criteria of the frailty
phenotype (grip strength, weight loss, exhaustion, walking speed, physical activity) were …

Frailty status at admission to hospital predicts multiple adverse outcomes

RE Hubbard, NM Peel, M Samanta, LC Gray… - Age and …, 2017 - academic.oup.com
Aims frailty is proposed as a summative measure of health status and marker of individual
vulnerability. We aimed to investigate the discriminative capacity of a frailty index (FI) …