The forced swim test (FST) is a behavioral test in rodents which was developed in 1978 by
Porsolt and colleagues as a model for predicting the clinical efficacy of antidepressant …

It has become increasingly apparent that women suffer a disproportionate amount of pain
during their lifetime compared to men. Over the past 15 years, a growing number of studies …

The focus of this chapter is the relationship between the onset of depression in women and
the reproductive events of the menopause transition. Epidemiologic studies have …

Depression is a major psychological disorder that contributes to global health problem. This
study aimed to evaluate the anti-depressant effect of Cerebrolysin (CBL) in Reserpine …

The neuroactive steroid allopregnanolone (ALLO) is an endogenous positive allosteric
modulator of GABA type A receptor (GABA AR), and the down-regulation of its biosynthesis …

Estrogen administration elicits anxiolytic and antidepressant-like effects in female rats;
however, the mechanism of this effect is unknown. Fatty acid amide hydrolase (FAAH), the …

Selective serotonin reuptake inhibitors (SSRIs), such as Prozac®, are used to treat mood
disorders. SSRIs attenuate (ie desensitize) serotonin 1A (5-HT1A) receptor signaling, as …

Abstract Background Regular," moderate", physical exercise is an established non-
pharmacological form of treatment for depressive disorders. Brain lateralization has a …

Pomegranate (Punica granatum) fruit is of particular interest because of its high nutritional
value and therapeutic actions. Recently, we showed that an aqueous extract of …

This study aimed to investigate the anti-depressant effect of hesperidin (Hsp) in
streptozotocin (STZ)-induced diabetic rats. Additionally, the effect of Hsp on hyperglycaemia …