Chitosan nanoparticles at the biological interface: implications for drug delivery
N Aibani, R Rai, P Patel, G Cuddihy, EK Wasan - Pharmaceutics, 2021 - mdpi.com
The unique properties of chitosan make it a useful choice for various nanoparticulate drug
delivery applications. Although chitosan is biocompatible and enables cellular uptake, its …
delivery applications. Although chitosan is biocompatible and enables cellular uptake, its …
Intestinal permeation enhancers for oral peptide delivery
S Maher, RJ Mrsny, DJ Brayden - Advanced drug delivery reviews, 2016 - Elsevier
Intestinal permeation enhancers (PEs) are one of the most widely tested strategies to
improve oral delivery of therapeutic peptides. This article assesses the intestinal permeation …
improve oral delivery of therapeutic peptides. This article assesses the intestinal permeation …
Recent advances in chitosan-based nanoparticles for oral delivery of macromolecules
Chitosan (CS), a cationic polysaccharide, is widely regarded as a safe and efficient intestinal
absorption enhancer of therapeutic macromolecules, owing to its inherent mucoadhesive …
absorption enhancer of therapeutic macromolecules, owing to its inherent mucoadhesive …
Biocompatibility of chitosan carriers with application in drug delivery
S Rodrigues, M Dionísio, C Remunan Lopez… - Journal of functional …, 2012 - mdpi.com
Chitosan is one of the most used polysaccharides in the design of drug delivery strategies
for administration of either biomacromolecules or low molecular weight drugs. For these …
for administration of either biomacromolecules or low molecular weight drugs. For these …
Polymeric nanoparticle drug delivery technologies for oral delivery applications
EM Pridgen, F Alexis, OC Farokhzad - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Many therapeutics are limited to parenteral administration. Oral administration
is a desirable alternative because of the convenience and increased compliance by …
is a desirable alternative because of the convenience and increased compliance by …
Scalable fabrication of size-controlled chitosan nanoparticles for oral delivery of insulin
Controlled delivery of protein would find diverse therapeutic applications. Formulation of
protein nanoparticles by polyelectrolyte complexation between the protein and a natural …
protein nanoparticles by polyelectrolyte complexation between the protein and a natural …
In vitro and in vivo models for the study of oral delivery of nanoparticles
Oral delivery is an attractive route to deliver therapeutics via nanoparticles due to its ease of
administration and patient compliance. This review discusses laboratory techniques for …
administration and patient compliance. This review discusses laboratory techniques for …
Parameters and characteristics governing cellular internalization and trans-barrier trafficking of nanostructures
Cellular internalization and trans-barrier transport of nanoparticles can be manipulated on
the basis of the physicochemical and mechanical characteristics of nanoparticles. Research …
the basis of the physicochemical and mechanical characteristics of nanoparticles. Research …
Dual chitosan/albumin-coated alginate/dextran sulfate nanoparticles for enhanced oral delivery of insulin
M Lopes, N Shrestha, A Correia, MA Shahbazi… - Journal of controlled …, 2016 - Elsevier
The potential of nanoparticles (NPs) to overcome the barriers for oral delivery of protein
drugs have led to the development of platforms capable of improving their bioavailability …
drugs have led to the development of platforms capable of improving their bioavailability …
Marine polysaccharides in pharmaceutical applications: Fucoidan and chitosan as key players in the drug delivery match field
AI Barbosa, AJ Coutinho, SA Costa Lima, S Reis - Marine Drugs, 2019 - mdpi.com
The use of marine-origin polysaccharides has increased in recent research because they
are abundant, cheap, biocompatible, and biodegradable. These features motivate their …
are abundant, cheap, biocompatible, and biodegradable. These features motivate their …