Toxicology and pharmacology of synthetic organoselenium compounds: An update
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …
compounds and some naturally occurring organoselenium amino acids. The use of …
Recent advances in polymer-based vaginal drug delivery systems
T Osmałek, A Froelich, B Jadach, A Tatarek… - Pharmaceutics, 2021 - mdpi.com
The vagina has been considered a potential drug administration route for centuries. Most of
the currently marketed and investigated vaginal formulations are composed with the use of …
the currently marketed and investigated vaginal formulations are composed with the use of …
Aerosolized nanoliposomal carrier of remdesivir: an effective alternative for COVID-19 treatment in vitro
Aim: To formulate an aerosolized nanoliposomal carrier for remdesivir (AL-Rem) against
coronavirus disease 2019. Methods: AL-Rem was prepared using modified hydration …
coronavirus disease 2019. Methods: AL-Rem was prepared using modified hydration …
Cetuximab-based PROteolysis targeting chimera for effectual downregulation of NSCLC with varied EGFR mutations
Abstract PROteolysis Targeting Chimeras (PROTACs) showed tremendous therapeutic
potential in degrading several oncoproteins including undruggable proteins. PROTACs are …
potential in degrading several oncoproteins including undruggable proteins. PROTACs are …
Implementation of Water‐Soluble Cyclodextrin‐Based Polymers in Biomedical Applications: How Far Are We?
Cyclodextrin‐based polymers can be prepared starting from the naturally occurring
monomers following green and low‐cost procedures. They can be selectively derivatized …
monomers following green and low‐cost procedures. They can be selectively derivatized …
Susceptibility of lung carcinoma cells to nanostructured lipid carrier of ARV-825, a BRD4 degrading proteolysis targeting chimera
The present work was aimed at developing an optimized and modified nanostructured lipid
carrier of BRD4 protein degrading Proteolysis Targeting Chimera (PROTAC) against non …
carrier of BRD4 protein degrading Proteolysis Targeting Chimera (PROTAC) against non …
Soluplus® as a solubilizing excipient for poorly water-soluble drugs: recent advances in formulation strategies and pharmaceutical product features
Since the emergence of Soluplus®(SOL) as a commercial graft copolymer, several
publications have been issued on its promising potential as a solubilizing excipient that …
publications have been issued on its promising potential as a solubilizing excipient that …
Cyclodextrin-based supramolecular ternary complexes: emerging role of ternary agents on drug solubility, stability, and bioavailability
P Suvarna, P Chaudhari… - Critical Reviews™ in …, 2022 - dl.begellhouse.com
The aqueous solubility of active drug moiety plays a crucial role in the development of an
efficacious formulation. The poor aqueous solubility of BCS class II and IV drugs is …
efficacious formulation. The poor aqueous solubility of BCS class II and IV drugs is …
Evaluation of the antifungal activity of an ebselen-loaded nanoemulsion in a mouse model of vulvovaginal candidiasis
Vulvovaginal candidiasis (VVC), caused by Candida albicans, is a common infection in
women affecting their quality of life. Standard antifungal drugs (eg, fluconazole …
women affecting their quality of life. Standard antifungal drugs (eg, fluconazole …
Enhancement in the therapeutic potential of lapatinib ditosylate against breast cancer by the use of β-cyclodextrin based ternary nanosponge system
The present investigation was performed to demonstrate the therapeutic potential of
lapatinib ditosylate (LD) loaded nanosponge for the treatment of breast cancer. The study …
lapatinib ditosylate (LD) loaded nanosponge for the treatment of breast cancer. The study …