Molecular pathogenesis of cholangiocarcinoma
PL Labib, G Goodchild, SP Pereira - BMC cancer, 2019 - Springer
Background Cholangiocarcinomas are a heterogeneous group of malignancies arising from
a number of cells of origin along the biliary tree. Although most cases in Western countries …
a number of cells of origin along the biliary tree. Although most cases in Western countries …
Intrahepatic cholangiocarcinoma: current perspectives
S Buettner, JLA van Vugt, JNM IJzermans… - OncoTargets and …, 2017 - Taylor & Francis
Intrahepatic cholangiocarcinoma (ICC) is the second most common malignancy arising from
the liver. ICC makes up about 10% of all cholangiocarcinomas. It arises from the peripheral …
the liver. ICC makes up about 10% of all cholangiocarcinomas. It arises from the peripheral …
Serum IL-6 and IL-8 correlate with prognostic factors in ovarian cancer
MMM Sanguinete, PHD Oliveira… - Immunological …, 2017 - Taylor & Francis
The aim of the study was to correlate serum levels of IL-2, IL-5, IL-6, IL-8, IL-10, and TNF-α
with clinical, laboratory, and pathological prognostic factors in patients with primary ovarian …
with clinical, laboratory, and pathological prognostic factors in patients with primary ovarian …
Patient-derived organoids of cholangiocarcinoma
CF Maier, L Zhu, LK Nanduri, D Kühn… - International journal of …, 2021 - mdpi.com
Cholangiocarcinoma (CC) is an aggressive malignancy with an inferior prognosis due to
limited systemic treatment options. As preclinical models such as CC cell lines are extremely …
limited systemic treatment options. As preclinical models such as CC cell lines are extremely …
[HTML][HTML] Precision medicine in cholangiocarcinoma
A Pellino, F Loupakis, M Cadamuro… - Translational …, 2018 - ncbi.nlm.nih.gov
Cholangiocarcinoma is one of the epithelial cancers with the poorest prognosis and the
narrowest therapeutic choice in humans. Compared with other cancer types …
narrowest therapeutic choice in humans. Compared with other cancer types …
Biomarkers and genetic markers of hepatocellular carcinoma and cholangiocarcinoma—what do we already know
J Baj, Ł Bryliński, F Woliński, M Granat, K Kostelecka… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma and cholangiocarcinoma continue to remain a
serious threat. In this review, we describe the most common biomarkers and genetic markers …
serious threat. In this review, we describe the most common biomarkers and genetic markers …
[HTML][HTML] The cholangiocyte primary cilium in health and disease
AP Mansini, E Peixoto, KM Thelen, C Gaspari… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Cholangiocytes, like most cells, express primary cilia extending from their membranes.
These organelles function as antennae which detect stimuli from bile and transmit the …
These organelles function as antennae which detect stimuli from bile and transmit the …
Transcription factor HIF1α promotes proliferation, migration, and invasion of cholangiocarcinoma via long noncoding RNA H19/microRNA-612/Bcl-2 axis
A Yu, L Zhao, Q Kang, J Li, K Chen, H Fu - Translational Research, 2020 - Elsevier
Cholangiocarcinoma, which is the most common invasive malignant tumor of the biliary tract,
has poor prognosis. There is evidence suggesting that hypoxia-inducible factor 1α (HIF1α) …
has poor prognosis. There is evidence suggesting that hypoxia-inducible factor 1α (HIF1α) …
Repeated resection for recurrent intrahepatic cholangiocarcinoma: A retrospective German multicentre study
F Bartsch, J Eberhard, F Rückert… - Liver …, 2021 - Wiley Online Library
Background Tumour recurrence is common after resection of intrahepatic
cholangiocarcinoma (ICC). Repeated resection is a potential curative treatment, but …
cholangiocarcinoma (ICC). Repeated resection is a potential curative treatment, but …
[HTML][HTML] Prognostic value and predication model of microvascular invasion in patients with intrahepatic cholangiocarcinoma
Z Tang, WR Liu, PY Zhou, ZB Ding, XF Jiang… - Journal of …, 2019 - ncbi.nlm.nih.gov
Background: Whether microvascular invasion (MVI) adversely influences oncological
outcomes for intrahepatic cholangiocarcinoma (ICC) patients remains unclear. The purpose …
outcomes for intrahepatic cholangiocarcinoma (ICC) patients remains unclear. The purpose …