Pre-, post-, and remote conditioning of the myocardium are well described adaptive
responses that markedly enhance the ability of the heart to withstand a prolonged …

Atherosclerotic plaques impair vascular function and can lead to arterial obstruction and
tissue ischaemia. Rupture of an atherosclerotic plaque within a coronary artery can result in …

The thioredoxin (Trx) system comprises Trx, truncated Trx (Trx-80), Trx reductase, and
NADPH, besides a natural Trx inhibitor, the thioredoxin-interacting protein (TXNIP). This …

One of the greatest examples of integrated signal transduction is revealed by examination of
effects mediated by AKT kinase in myocardial biology. Positioned at the intersection of …

Diet-induced hypercholesterolemia leads to oxidative/nitrative stress and subsequent
myocardial dysfunction. However, the regulatory role of microRNAs in this phenomenon is …

Hypercholesterolemia is a frequent metabolic disorder associated with increased risk for
cardiovascular morbidity and mortality. In addition to its well‐known proatherogenic effect …

The morbidity and mortality from cardiovascular diseases (CVD) remain high. Metabolic
diseases such as obesity, hyperlipidemia, diabetes mellitus (DM), non-alcoholic fatty liver …

Hyperlipidaemia is a well‐established risk factor for cardiovascular diseases and therefore,
many animal model have been developed to mimic the human abnormal elevation of blood …

Background In earlier studies, the supplementation of the natural compound Naringenin
(NGEN), improved the liver oxidative and inflammatory status, which indicates its direct effect …

Hypercholesterolaemia is considered to be a principle risk factor for cardiovascular disease,
having direct negative effects on the myocardium itself, in addition to the development of …