A review of 65 studies of individuals with schizophrenia who had never been treated with
antipsychotic medications indicates significant abnormalities in brain structure and function …

“Atypical” antipsychotic agents (AAPs) are used to treat the symptoms of schizophrenia and
bipolar mania. In general, AAPs produce antipsychotic responses with fewer acute …

OBJECTIVE: The basal ganglia may contribute to extrapyramidal movement disorders,
affective disturbances, and cognitive deficits in schizophrenia. Basal ganglia volumes are …

OBJECTIVE: The study examined the primary versus secondary character of negative
symptoms in a group of first-episode, neuroleptic-naive psychotic patients before and after …

Patients with first-episode schizophrenia appear to respond to lower doses of neuroleptics,
and to be more sensitive to developing extrapyramidal side-effects. The authors therefore …

BACKGROUND: Primary neuromotor abnormalities are thought to be a manifestation of the
brain pathology underlying the psychotic illness; however, their causes and consequences …

Objective: To examine the effect of antipsychotic medication on neuromotor abnormalities in
a sample of psychotic patients never exposed to antipsychotic drugs. Method: One hundred …

Abstract" All-causes discontinuation" refers to discontinuation of treatment for any reason,
and adherence to medication is an important component of this measure. Two recent …

Movement disorders in first-episode psychosis are increasingly recognized; however, the
prevalence and clinical correlates areuncertain. We compared antipsychotic exposed (< 12 …

Background: To study the interrelationship pattern of negative, depressive, parkinsonian and
catatonic symptoms over an exacerbation phase of schizophrenia. Method: Forty-five …