Implantable cardioverter-defibrillator in patients with inherited arrhythmia syndromes: A systematic review

P Medeiros, M Santos, C Arantes, VH Pereira, S Rocha - Heart & Lung, 2023 - Elsevier
Background The potential benefit of implantable cardioverter-defibrillator (ICD) therapy in
individuals with inherited arrhythmia syndromes is well known. However, it is not deprived of …

Territory-wide cohort study of Brugada syndrome in Hong Kong: predictors of long-term outcomes using random survival forests and non-negative matrix factorisation

S Lee, J Zhou, KHC Li, KSK Leung, I Lakhani, T Liu… - Open …, 2021 - openheart.bmj.com
Objectives Brugada syndrome (BrS) is an ion channelopathy that predisposes affected
patients to spontaneous ventricular tachycardia/fibrillation (VT/VF) and sudden cardiac …

[HTML][HTML] Attendance-related healthcare resource utilisation and costs in patients with Brugada syndrome in Hong Kong: a retrospective cohort study

S Lee, CT Chung, OHI Chou, TTL Lee… - Current problems in …, 2023 - Elsevier
Understanding health care resource utilisation and its associated costs are important for
identifying areas of improvement regarding resource allocations. However, there is limited …

Territory-wide Chinese cohort of long QT syndrome: random survival forest and Cox analyses

G Tse, S Lee, J Zhou, T Liu, ICK Wong… - Frontiers in …, 2021 - frontiersin.org
Introduction: Congenital long QT syndrome (LQTS) is a cardiac ion channelopathy that
predisposes affected individuals to spontaneous ventricular tachycardia/fibrillation (VT/VF) …

Incorporating latent variables using nonnegative matrix factorization improves risk stratification in Brugada syndrome

G Tse, J Zhou, S Lee, T Liu, G Bazoukis… - Journal of the …, 2020 - Am Heart Assoc
Background A combination of clinical and electrocardiographic risk factors is used for risk
stratification in Brugada syndrome. In this study, we tested the hypothesis that the …

Subcutaneous versus transvenous implantable cardioverter-defibrillator among drug-induced type-1 ECG pattern Brugada syndrome: a propensity score matching …

V Russo, A Caturano, F Guerra, F Migliore, G Mascia… - Heart and Vessels, 2023 - Springer
No real-world data are available about the complications rate in drug-induced type 1
Brugada Syndrome (BrS) patients with an implantable cardioverter-defibrillator (ICD). Aim of …

Identification of novel SCN5A single nucleotide variants in Brugada syndrome: A territory-wide study from Hong Kong

G Tse, S Lee, T Liu, HC Yuen, ICK Wong… - Frontiers in …, 2020 - frontiersin.org
Background The aim of this study is to report on the genetic composition of Brugada
syndrome (BrS) patients undergoing genetic testing in Hong Kong. Methods Patients with …

Late life‐threatening arrhythmia in patients with Brugada syndrome: Results from long‐term follow‐up in a large Japanese cohort

T Shinohara, M Takagi, T Kamakura… - Journal of …, 2024 - Wiley Online Library
Abstract Introduction Most patients with Brugada syndrome (BrS) are first diagnosed in their
40s, with sudden cardiac death (SCD) often occurring in their 50s. Ventricular fibrillation (VF) …

Temporal variability in electrocardiographic indices in subjects with Brugada patterns

S Lee, J Zhou, T Liu, KP Letsas, SS Hothi… - Frontiers in …, 2020 - frontiersin.org
Introduction Patients with Brugada electrocardiographic (ECG) patterns have differing levels
of arrhythmic risk. We hypothesized that temporal variations in certain ECG markers may …

Historical perspective and recent progress in cardiac ion channelopathies research and clinical practice in Hong Kong

KSK Leung, H Huang, CT Chung, D Radford… - International Journal of …, 2023 - Springer
Cardiac ion channelopathies encompass a set of inherited or acquired conditions that are
due to dysfunction in ion channels or their associated proteins, typically in the presence of …