Background Articular cartilage defects are a veritable therapeutic problem because
therapeutic options are very scarce. Due to the poor self-regeneration capacity of cartilage …

Background: Following successful preclinical studies, stem cell therapy is emerging as a
candidate for the treatment of articular cartilage lesions. Because stem cell therapy for …

This review provides a brief synopsis of the anatomy and physiology of the osteochondral
interface, scaffold-based and non-scaffold based approaches for engineering both tissues …

The goal of tissue engineering is to create a functional replacement for tissues damaged by
injury or disease. In many cases, impaired tissues cannot provide viable cells, leading to the …

Cartilage tissue engineering is an emerging technique for the regeneration of cartilage
tissue damaged as a result of trauma or disease. As the propensity for healing and …

The clinical efficacy of ESWT in treating bone non union has been widely recognized, but
the biological mechanism of ESWT promoting bone non union healing is still unclear. ESWT …

Animal cells have served as highly controllable model systems for furthering cartilage tissue
engineering practices in pursuit of treating osteoarthritis. Although successful strategies for …

Heterotopic ossification (HO) is a common, potentially debilitating pathology that is
instigated by inflammation caused by tissue damage or other insults, which is followed by …

Introduction: The production of functional alternatives to bone autografts and the
development new treatment strategies for cartilage defects are great challenges that could …

Umbilical cord blood (UCB) is an attractive alternative to bone marrow for isolation of
mesenchymal stem cells (MSCs) to treat articular cartilage defects. Here, we set out to …