Plant phenolics: Bioavailability as a key determinant of their potential health-promoting applications

P Cosme, AB Rodríguez, J Espino, M Garrido - Antioxidants, 2020 - mdpi.com
Phenolic compounds are secondary metabolites widely spread throughout the plant
kingdom that can be categorized as flavonoids and non-flavonoids. Interest in phenolic …

Recent advances on the improvement of quercetin bioavailability

K Kandemir, M Tomas, DJ McClements… - Trends in Food Science & …, 2022 - Elsevier
Background Natural antioxidants, such as polyphenols, are finding increasing application in
functional foods designed to improve human health, wellbeing, and performance. Quercetin …

Biopolymer nano-particles and natural nano-carriers for nano-encapsulation of phenolic compounds

AF Esfanjani, SM Jafari - Colloids and Surfaces B: Biointerfaces, 2016 - Elsevier
Phenolic compounds are major micronutrients in our diet, 1 and evidence for their role in the
prevention of degenerative diseases such as cancer, inflammation and neurodegenerative …

Strategies to address low drug solubility in discovery and development

HD Williams, NL Trevaskis, SA Charman… - Pharmacological …, 2013 - Elsevier
Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Novel drug delivery systems for loading of natural plant extracts and their biomedical applications

HS Rahman, HH Othman, NI Hammadi… - International journal …, 2020 - Taylor & Francis
Many types of research have distinctly addressed the efficacy of natural plant metabolites
used for human consumption both in cell culture and preclinical animal model systems …

The flavonoid quercetin in disease prevention and therapy: facts and fancies

M Russo, C Spagnuolo, I Tedesco, S Bilotto… - Biochemical …, 2012 - Elsevier
Biochemical and genetic studies on cellular and animal models on the mechanism (s) of
action of phytochemicals provide a functional explanation of how and why a diet rich in fruits …

Solution blow spun bilayer chitosan/polylactic acid nanofibrous patch with antibacterial and anti-inflammatory properties for accelerating acne healing

B Yang, B Tang, Z Wang, F Feng, G Wang, Z Zhao… - Carbohydrate …, 2024 - Elsevier
The quercetin (QC) loaded chitosan (CS) nanofibrous patch (CS QC) was designed and
fabricated successfully by solution blow spinning (SBS). And it was employed to explore a …

Synergic formulation of onion peel quercetin loaded chitosan-cellulose hydrogel with green zinc oxide nanoparticles towards controlled release, biocompatibility …

D George, PU Maheswari, KMMS Begum - International journal of …, 2019 - Elsevier
The therapeutic prospective of a novel carrier based delivery of phyto-derived quercetin
(QE) extracted from onion peel waste was studied in the present work. Dialdehyde cellulose …

[HTML][HTML] Application of quercetin flavonoid based hybrid nanocomposites: A review

B Parhi, D Bharatiya, SK Swain - Saudi Pharmaceutical Journal, 2020 - Elsevier
Natural bioflavonoids are an essential component of dietary supplements possessing
antimicrobial properties. Many of the bioflavonoids have resulted in positive antitumor …

[HTML][HTML] Recent developments of nanostructures for the ocular delivery of natural compounds

MS Razavi, P Ebrahimnejad, Y Fatahi… - Frontiers in …, 2022 - frontiersin.org
Ocular disorders comprising various diseases of the anterior and posterior segments are
considered as the main reasons for blindness. Natural products have been identified as …