A perspective on active glassy dynamics in biological systems
Dynamics is central to living systems. Many experiments in the last two decades have
revealed glassy dynamics in diverse biological systems, showing a transition between a …
revealed glassy dynamics in diverse biological systems, showing a transition between a …
Theory of the center-of-mass diffusion and viscosity of microstructured and variable sequence copolymer liquids
G Shi, KS Schweizer - Soft matter, 2023 - pubs.rsc.org
Biomolecular condensates formed through the phase separation of proteins and nucleic
acids are widely observed, offering a fundamental means of organizing intracellular …
acids are widely observed, offering a fundamental means of organizing intracellular …
[PDF][PDF] Molecular Drivers of Aging in Biomolecular Condensates: Desolvation, Rigidification, and Sticker Lifetimes
S Biswas, DA Potoyan - PRX Life, 2024 - APS
Biomolecular condensates are dynamic intracellular entities defined by their sequence-and
composition-encoded material properties. During aging, these properties can change …
composition-encoded material properties. During aging, these properties can change …
Sequence complexity and monomer rigidity control the morphologies and aging dynamics of protein aggregates
R Takaki, D Thirumalai - Proceedings of the National Academy of …, 2024 - pnas.org
Understanding the biophysical basis of protein aggregation is important in biology because
of the potential link to several misfolding diseases. Although experiments have shown that …
of the potential link to several misfolding diseases. Although experiments have shown that …
Bringing Together Two Paradigms of Nonequilibrium: Fragile versus Robust Aging in Driven Glassy Systems
There are two key paradigms for nonequilibrium dynamics: on the one hand, aging toward
an equilibrium state that cannot be reached on reasonable timescales; on the other, external …
an equilibrium state that cannot be reached on reasonable timescales; on the other, external …
Dynamically arrested condensate fusion creates complex structures with varying material properties
NA Erkamp, IA Sanchez-Burgos, A Zhou, TJ Krug… - bioRxiv, 2024 - biorxiv.org
The cell nucleus and cytosol contain numerous biomolecular condensates which
dynamically reshape, fuse and split to accomplish precise compartmentalization of the cell …
dynamically reshape, fuse and split to accomplish precise compartmentalization of the cell …
Bringing together two paradigms of non-equilibrium: Driven dynamics of aging systems
D Tapias, C Marteau, F Aguirre-López… - arXiv preprint arXiv …, 2024 - arxiv.org
There are two fundamental paradigms for non-equilibrium dynamics: on the one hand, aging
towards an equilibrium state that cannot be reached on reasonable timescales; on the other …
towards an equilibrium state that cannot be reached on reasonable timescales; on the other …
Microscopic model for aging of biocondensates
HL Roy, PDL Rios - arXiv preprint arXiv:2407.21710, 2024 - arxiv.org
Biomolecular condensates are membraneless compartments in the cell that are involved in
a wide diversity of biological processes. These phase-separated droplets usually exhibit a …
a wide diversity of biological processes. These phase-separated droplets usually exhibit a …
Charge distribution of coating brush drives inter-chromosome attraction
The condensation of charged polymers is an important driver for the formation of
biomolecular condensates. Recent experiments suggest that this mechanism also controls …
biomolecular condensates. Recent experiments suggest that this mechanism also controls …
Collective Processes In Cellular Reprogramming
A Mohammadzadehhashtroud - 2024 - tud.qucosa.de
Abstract (EN) Epigenetics comprises chemical modifications of the DNA and the proteins
that the DNA is wrapped around them. These modifications play key roles in establishing …
that the DNA is wrapped around them. These modifications play key roles in establishing …