Ancistrolikokine E3, a 5,8′-Coupled Naphthylisoquinoline Alkaloid, Eliminates the Tolerance of Cancer Cells to Nutrition Starvation by Inhibition of the Akt/mTOR …
PANC-1 human pancreatic cancer cells are characterized by their ability to proliferate
aggressively under hypovascular and hypoxic conditions in the tumor microenvironment …
aggressively under hypovascular and hypoxic conditions in the tumor microenvironment …
A pharmacognostic approach for mitigating pancreatic cancer: emphasis on herbal extracts and phytoconstituents
S Gupta, A Kumar, KK Tejavath - Future Journal of Pharmaceutical …, 2021 - Springer
Background Pancreatic cancer is studied as one of the most lethal cancers with currently no
control of its lethality, mainly due to its late diagnosis and lack of foolproof treatment …
control of its lethality, mainly due to its late diagnosis and lack of foolproof treatment …
Design and synthesis of functionalized coumarins as potential anti-austerity agents that eliminates cancer cells' tolerance to nutrition starvation
Human pancreatic tumor cells have inherent ability to tolerate nutrition starvation which
enables them to survive in the hypovascular tumor microenvironment. Discovery of agents …
enables them to survive in the hypovascular tumor microenvironment. Discovery of agents …
Structure-activity relationship and mechanistic study on guggulsterone derivatives; Discovery of new anti-pancreatic cancer candidate
A Kohyama, MJ Kim, R Yokoyama, S Sun… - Bioorganic & Medicinal …, 2022 - Elsevier
Pancreatic cancer is one of the deadliest types of malignancies. A new intervention aiming
to combat pancreatic cancer is targeting its extra-ordinary ability to tolerate nutrition …
to combat pancreatic cancer is targeting its extra-ordinary ability to tolerate nutrition …
Chemical Constituents of Callistemon subulatus and Their Anti-Pancreatic Cancer Activity against Human PANC-1 Cell Line
J Maneenet, AM Tawila, AM Omar, ND Phan, C Ojima… - Plants, 2022 - mdpi.com
An n-hexane extract of Callistemon subulatus was found to exhibit potent cytotoxicity against
PANC-1 human pancreatic cancer cells, preferentially under nutrition starvation conditions …
PANC-1 human pancreatic cancer cells, preferentially under nutrition starvation conditions …
Alkaloids and styryllactones from Goniothalamus cheliensis
Eight previously undescribed compounds, including four alkaloids and five styryllactones
together with 36 known compounds were isolated from the twig and leaf extracts of …
together with 36 known compounds were isolated from the twig and leaf extracts of …
A new anti-austerity agent, 4′-O-methylgrynullarin from Derris scandens induces PANC-1 human pancreatic cancer cell death under nutrition starvation via inhibition …
S Sun, DF Dibwe, MJ Kim, AM Omar, ND Phan… - Bioorganic & Medicinal …, 2021 - Elsevier
An ethanolic extract of Derris scandens flowers showed potent preferential cytotoxicity
against PANC-1 human pancreatic cancer cells under nutrient-deprived condition, with a PC …
against PANC-1 human pancreatic cancer cells under nutrient-deprived condition, with a PC …
(R)-3-(8'-Hydroxyfarnesyl)-indole and other chemical constituents from the flowers of Anomianthus dulcis and their antimalarial and cytotoxic activities
T Promchai, T Thaima, R Rattanajak… - Natural Product …, 2021 - Taylor & Francis
Abstract A new farnesylindole,(R)-3-(8'-hydroxyfarnesyl)-indole (1), as a scalemic mixture
(33% ee) along with nine known compounds (2-10), including one farnesylindole, three …
(33% ee) along with nine known compounds (2-10), including one farnesylindole, three …
Synthesis of guggulsterone derivatives as potential anti-austerity agents against PANC-1 human pancreatic cancer cells
A Kohyama, R Yokoyama, DF Dibwe… - Bioorganic & Medicinal …, 2020 - Elsevier
E-and Z-guggulsterones and nine guggulsterone derivatives (GSDs) were synthesized and
evaluated for their preferential cytotoxicity against human PANC-1 cell in nutrient deprived …
evaluated for their preferential cytotoxicity against human PANC-1 cell in nutrient deprived …
A divergent and stereoselective approach for the syntheses of (–)-zeylenol,(+)-6-O-benzoylzeylenol,(+)-uvarigranol E and (+)-uvarigranol F
A Vinaykumar, BV Rao - Carbohydrate Research, 2021 - Elsevier
A common, divergent, efficient, and stereoselective approach to the total syntheses of four
carbasugars, namely,(–)-zeylenol,(+)-6-O-benzoylzeylenol,(+)-uvarigranol E and (+) …
carbasugars, namely,(–)-zeylenol,(+)-6-O-benzoylzeylenol,(+)-uvarigranol E and (+) …