With the growing number of genetic association studies, the genotype-phenotype atlas has
become increasingly more complex, yet the functional consequences of most disease …

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Hypertension continues to be a major risk factor for global mortality, and recent genome-
wide association studies (GWAS) have expanded in size, leading to the identification of …

Despite substantial progress in treatment and control, hypertension still ac-counts for 10% of
the population attributable risk for all-cause mortality in most societies. 1 In addition to better …

Maternal blood pressure (BP) is associated with variations in fetal weight, an important
determinant of neonatal and adult health. However, the association of BP-raising genetic …

Although multiple lifestyle exposures simultaneously impact blood pressure (BP) and
cardiovascular health, most analysis so far has considered each single lifestyle exposure …

Background Over the last 10 years, there have been over 3300 genome-wide association
studies (GWAS). Almost every GWAS study provides a Manhattan plot either as a main …

Hundreds of loci have been associated with blood pressure (BP) traits from many genome-
wide association studies. We identified an enrichment of these loci in aorta and tibial artery …

Background: Cardiovascular disease (CVD) is a complex disease, and genetic factors
contribute individually or cumulatively to CVD risk. While African American women and men …

Linear regression is a standard approach to identify genetic variants associated with
continuous traits in genome‐wide association studies (GWAS). In a standard epidemiology …