Nausea and vomiting of pregnancy (NVP) is a common condition that affects up to 70% of
pregnant women. Hyperemesis gravidarum (HG) is considered the serious form of NVP …

The rate of gastric emptying is a critical determinant of postprandial glycaemia and,
accordingly, is fundamental to maintaining blood glucose homeostasis. Disordered gastric …

Background Metoclopramide is a dopamine receptor antagonist which has been used for
treatment of a variety of gastrointestinal symptoms over the last thirty years. In 2009, the FDA …

Background & Aims Gastroparesis is a complication of diabetes with few treatment options.
Relamorelin (also referred to as RM-131) is a selective, prokinetic agonist of ghrelin. We …

Diabetic gastroparesis is a disorder that occurs in both type 1 and type 2 diabetes. It is
associated with considerable morbidity among these patients and with the resultant …

Tardive syndromes are a group of hyperkinetic and hypokinetic movement disorders that
occur after some delay following exposure to dopamine receptor blocking agents such as …

Nausea is an uneasy feeling in the stomach while vomiting refers to the forceful expulsion of
gastric contents. Chronic nausea and vomiting represent a diverse array of disorders …

Tardive dyskinesia (TD) is a serious, often disabling, movement disorder that is caused by
medications that block dopamine receptors (ie, neuroleptics, anti-emetics). There is currently …

BACKGROUND: Movement disorders are a group of neurological motor disturbances
manifested by either paucity or slowness of movement, such as seen in Parkinson's disease …

Background Metoclopramide is primarily a dopamine receptor antagonist, with 5HT3
receptor antagonist and 5HT4 receptor agonist activity, and used as an antiemetic and …