[HTML][HTML] Origin and function of the yolk sac in primate embryogenesis

C Ross, TE Boroviak - Nature communications, 2020 - nature.com
Human embryogenesis is hallmarked by two phases of yolk sac development. The primate
hypoblast gives rise to a transient primary yolk sac, which is rapidly superseded by a …

The primitive streak and cellular principles of building an amniote body through gastrulation

G Sheng, A Martinez Arias, A Sutherland - Science, 2021 - science.org
BACKGROUND Pluripotent cells are generated by embryonic divisions that occur shortly
after fertilization. These cells are transformed into the recognizable outline of an organism …

[HTML][HTML] Gastruloids: Pluripotent stem cell models of mammalian gastrulation and embryo engineering

AM Arias, Y Marikawa, N Moris - Developmental biology, 2022 - Elsevier
Gastrulation is a fundamental and critical process of animal development whereby the mass
of cells that results from the proliferation of the zygote transforms itself into a recognizable …

[HTML][HTML] A hexa-species transcriptome atlas of mammalian embryogenesis delineates metabolic regulation across three different implantation modes

A Malkowska, C Penfold, S Bergmann… - Nature …, 2022 - nature.com
Mammalian embryogenesis relies on glycolysis and oxidative phosphorylation to balance
the generation of biomass with energy production. However, the dynamics of metabolic …

Alternative mammalian strategies leading towards gastrulation: losing polar trophoblast (Rauber's layer) or gaining an epiblast cavity

PL Pfeffer - … Transactions of the Royal Society B, 2022 - royalsocietypublishing.org
Using embryological data from 14 mammalian orders, the hypothesis is presented that in
placental mammals, epiblast cavitation and polar trophoblast loss are alternative …

The hypoblast (visceral endoderm): an evo-devo perspective

CD Stern, KM Downs - Development, 2012 - journals.biologists.com
When amniotes appeared during evolution, embryos freed themselves from intracellular
nutrition; development slowed, the mid-blastula transition was lost and maternal …

[HTML][HTML] Conserved features of non-primate bilaminar disc embryos and the germline

R Alberio, T Kobayashi, MA Surani - Stem cell reports, 2021 - cell.com
Post-implantation embryo development commences with a bilaminar disc in most mammals,
including humans. Whereas access to early human embryos is limited and subject to greater …

Major transcriptomic, epigenetic and metabolic changes underlie the pluripotency continuum in rabbit preimplantation embryos

W Bouchereau, L Jouneau, C Archilla, I Aksoy… - …, 2022 - journals.biologists.com
Despite the growing interest in the rabbit model for developmental and stem cell biology, the
characterization of embryos at the molecular level is still poorly documented. We conducted …

[HTML][HTML] Morphological and gene expression changes in cattle embryos from hatched blastocyst to early gastrulation stages after transfer of in vitro produced embryos

J van Leeuwen, DK Berg, PL Pfeffer - PloS one, 2015 - journals.plos.org
A detailed morphological staging system for cattle embryos at stages following blastocyst
hatching and preceding gastrulation is presented here together with spatiotemporal …

Why machine-information metaphors are bad for science and science education

M Pigliucci, M Boudry - Science & Education, 2011 - Springer
Genes are often described by biologists using metaphors derived from computational
science: they are thought of as carriers of information, as being the equivalent of “blueprints” …