Metabolomics has emerged as an invaluable tool that can be used along with genomics,
transcriptomics and proteomics to understand host–pathogen interactions at small-molecule …

Lipid droplets (LDs) are commonly found in various biological cells and are organelles
related to cell metabolism. LDs, the number and size of which are heterogeneous across cell …

Metabolomics-driven discoveries of biological samples remain hampered by the grand
challenge of metabolite annotation and identification. Only few metabolites have an …

The microbial community plays an important role on the solid-state fermentation (SSF) of
Chinese cereal vinegar, where acetic acid bacteria (AAB) and lactic acid bacteria (LAB) are …

Apple ring rot caused by Botryosphaeria dothidea is an economically significant plant
disease that spreads across the apple production areas in China. The pathogen infects …

The alarming increase in multi-and extensively drug-resistant (MDR and XDR) strains of
Mycobacterium tuberculosis (MTB) has triggered the scientific community to search for …

Drug metabolism is generally associated with liver enzymes. However, in the case of
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), Mtb-mediated …

Nitrogen metabolism is an important physiological process that affects the survival and
virulence of Mycobacterium tuberculosis. M. tuberculosis's utilization of nitrogen in the …

Mycobacterium tuberculosis (Mtb) causes chronic granulomatous lung disease in humans.
Recently, novel strategies such as host-directed therapeutics and adjunctive therapies that …

Current tools to annotate protein function have failed to keep pace with the speed of DNA
sequencing and exponentially growing number of proteins of unknown function (PUFs). A …