Fluorescent probes for lipid membranes: from the cell surface to organelles
AS Klymchenko - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus Biomembranes are ubiquitous lipid structures that delimit the cell surface and
organelles and operate as platforms for a multitude of biomolecular processes. The …
organelles and operate as platforms for a multitude of biomolecular processes. The …
Photobleaching of organic fluorophores: quantitative characterization, mechanisms, protection
AP Demchenko - Methods and applications in fluorescence, 2020 - iopscience.iop.org
Photochemical stability is one of the most important parameters that determine the
usefulness of organic dyes in different applications. This Review addresses key factors that …
usefulness of organic dyes in different applications. This Review addresses key factors that …
Targeted solvatochromic fluorescent probes for imaging lipid order in organelles under oxidative and mechanical stress
DI Danylchuk, PH Jouard… - Journal of the American …, 2021 - ACS Publications
Biomembranes constitute a basis for all compartments of live cells, and therefore, the
monitoring of their lipid organization is essential for understanding cell status and activity …
monitoring of their lipid organization is essential for understanding cell status and activity …
Design and application of fluorescent probes to detect cellular physical microenvironments
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …
subcellular compartments, living cells, and organisms. In particular, physical properties …
Solvatochromic and fluorogenic dyes as environment-sensitive probes: design and biological applications
AS Klymchenko - Accounts of chemical research, 2017 - ACS Publications
Conspectus Fluorescent environment-sensitive probes are specially designed dyes that
change their fluorescence intensity (fluorogenic dyes) or color (eg, solvatochromic dyes) in …
change their fluorescence intensity (fluorogenic dyes) or color (eg, solvatochromic dyes) in …
Large Stokes shift benzothiazolium cyanine dyes with improved intramolecular charge transfer (ICT) for cell imaging applications
CS Abeywickrama - Chemical Communications, 2022 - pubs.rsc.org
Intramolecular Charge Transfer (ICT) is a crucial photophysical phenomenon that can be
used to improve the Stokes' shift in fluorescent dyes. The introduction of molecular …
used to improve the Stokes' shift in fluorescent dyes. The introduction of molecular …
Principles of aggregation‐induced emission: design of deactivation pathways for advanced AIEgens and applications
Twenty years ago, the concept of aggregation‐induced emission (AIE) was proposed, and
this unique luminescent property has attracted scientific interest ever since. However, AIE …
this unique luminescent property has attracted scientific interest ever since. However, AIE …
Ferroptosis mediates cuprizone-induced loss of oligodendrocytes and demyelination
Multiple sclerosis (MS) is a chronic demyelinating disease of the CNS. Cuprizone (CZ), a
copper chelator, is widely used to study demyelination and remyelination in the CNS, in the …
copper chelator, is widely used to study demyelination and remyelination in the CNS, in the …
Recent advances in fluorescent probes for lipid droplets
Lipid droplets (LDs) are organelles that serve as the storage of intracellular neutral lipids.
LDs regulate many physiological processes. They recently attracted attention after extensive …
LDs regulate many physiological processes. They recently attracted attention after extensive …
Mechanosensitive fluorescent probes to image membrane tension in mitochondria, endoplasmic reticulum, and lysosomes
Measuring forces inside cells is particularly challenging. With the development of
quantitative microscopy, fluorophores which allow the measurement of forces became highly …
quantitative microscopy, fluorophores which allow the measurement of forces became highly …