Plasmids are important “vehicles” for the communication of genetic information between
bacteria. The exchange of plasmids transmits pathogenically and environmentally relevant …

Syphilis is a chronic sexually transmitted disease caused by Treponema pallidum subsp.
pallidum. Clinical manifestations separate the disease into stages; late stages of disease are …

Bacterial small RNAs (sRNAs) have been implicated in various aspects of post-
transcriptional gene regulation. Here, we demonstrate that sRNAs also act at the level of …

Here we investigate the dynamics of the hepatic intravascular immune response to a
pathogen relevant to invariant natural killer T cells (i NKT cells). Immobilized Kupffer cells …

Outer surface protein C (OspC) is a differentially expressed major surface lipoprotein of
Borrelia burgdorferi. ospC is swiftly upregulated when spirochetes leave the Ixodes …

The molecular basis of how Borrelia burgdorferi (Bb), the Lyme disease spirochete,
maintains itself in nature via a complex life cycle in ticks and mammals is poorly understood …

Borrelia burgdorferi is the etiologic agent of Lyme disease, the most prevalent arthropod-
borne disease in the United States. The genome of the type strain, B31, consists of a …

The spirochetes in the Borrelia burgdorferi sensu lato genospecies group cycle in nature
between tick vectors and vertebrate hosts. The current assemblage of B. burgdorferi sensu …

Lyme disease is the most common tick-borne human illness in North America. In order to
understand the molecular pathogenesis, natural diversity, population structure and epizootic …

Pathogenic spirochetes are bacteria that cause a number of emerging and re-emerging
diseases worldwide, including syphilis, leptospirosis, relapsing fever, and Lyme borreliosis …