Genomics of microbial plasmids: classification and identification based on replication and transfer systems and host taxonomy
M Shintani, ZK Sanchez, K Kimbara - Frontiers in microbiology, 2015 - frontiersin.org
Plasmids are important “vehicles” for the communication of genetic information between
bacteria. The exchange of plasmids transmits pathogenically and environmentally relevant …
bacteria. The exchange of plasmids transmits pathogenically and environmentally relevant …
Biological basis for syphilis
RE LaFond, SA Lukehart - Clinical microbiology reviews, 2006 - Am Soc Microbiol
Syphilis is a chronic sexually transmitted disease caused by Treponema pallidum subsp.
pallidum. Clinical manifestations separate the disease into stages; late stages of disease are …
pallidum. Clinical manifestations separate the disease into stages; late stages of disease are …
sRNA-mediated control of transcription termination in E. coli
N Sedlyarova, I Shamovsky, BK Bharati, V Epshtein… - Cell, 2016 - cell.com
Bacterial small RNAs (sRNAs) have been implicated in various aspects of post-
transcriptional gene regulation. Here, we demonstrate that sRNAs also act at the level of …
transcriptional gene regulation. Here, we demonstrate that sRNAs also act at the level of …
An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells
WY Lee, TJ Moriarty, CHY Wong, H Zhou… - Nature …, 2010 - nature.com
Here we investigate the dynamics of the hepatic intravascular immune response to a
pathogen relevant to invariant natural killer T cells (i NKT cells). Immobilized Kupffer cells …
pathogen relevant to invariant natural killer T cells (i NKT cells). Immobilized Kupffer cells …
OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands
Outer surface protein C (OspC) is a differentially expressed major surface lipoprotein of
Borrelia burgdorferi. ospC is swiftly upregulated when spirochetes leave the Ixodes …
Borrelia burgdorferi. ospC is swiftly upregulated when spirochetes leave the Ixodes …
Essential role for OspA/B in the life cycle of the Lyme disease spirochete
The molecular basis of how Borrelia burgdorferi (Bb), the Lyme disease spirochete,
maintains itself in nature via a complex life cycle in ticks and mammals is poorly understood …
maintains itself in nature via a complex life cycle in ticks and mammals is poorly understood …
Profiling of Temperature-Induced Changes in Borrelia burgdorferi Gene Expression by Using Whole Genome Arrays
C Ojaimi, C Brooks, S Casjens, P Rosa… - Infection and …, 2003 - Am Soc Microbiol
Borrelia burgdorferi is the etiologic agent of Lyme disease, the most prevalent arthropod-
borne disease in the United States. The genome of the type strain, B31, consists of a …
borne disease in the United States. The genome of the type strain, B31, consists of a …
Genetics of Borrelia burgdorferi
D Brisson, D Drecktrah, CH Eggers… - Annual review of …, 2012 - annualreviews.org
The spirochetes in the Borrelia burgdorferi sensu lato genospecies group cycle in nature
between tick vectors and vertebrate hosts. The current assemblage of B. burgdorferi sensu …
between tick vectors and vertebrate hosts. The current assemblage of B. burgdorferi sensu …
Genome Stability of Lyme Disease Spirochetes: Comparative Genomics of Borrelia burgdorferi Plasmids
Lyme disease is the most common tick-borne human illness in North America. In order to
understand the molecular pathogenesis, natural diversity, population structure and epizootic …
understand the molecular pathogenesis, natural diversity, population structure and epizootic …
Real-time high resolution 3D imaging of the lyme disease spirochete adhering to and escaping from the vasculature of a living host
TJ Moriarty, MU Norman, P Colarusso… - PLoS …, 2008 - journals.plos.org
Pathogenic spirochetes are bacteria that cause a number of emerging and re-emerging
diseases worldwide, including syphilis, leptospirosis, relapsing fever, and Lyme borreliosis …
diseases worldwide, including syphilis, leptospirosis, relapsing fever, and Lyme borreliosis …