[HTML][HTML] Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans

K Pafili, M Roden - Molecular Metabolism, 2021 - Elsevier
Background Nonalcoholic fatty liver disease (NAFLD) comprises hepatic alterations with
increased lipid accumulation (steatosis) without or with inflammation (nonalcoholic …

[HTML][HTML] Ketogenic diets and chronic disease: weighing the benefits against the risks

L Crosby, B Davis, S Joshi, M Jardine, J Paul… - Frontiers in …, 2021 - frontiersin.org
Very-low-carbohydrate ketogenic diets have been long been used to reduce seizure
frequency and more recently have been promoted for a variety of health conditions …

Overview of non-alcoholic fatty liver disease (NAFLD) and the role of sugary food consumption and other dietary components in its development

P Vancells Lujan, E Vinas Esmel… - Nutrients, 2021 - mdpi.com
NAFLD is the world's most common chronic liver disease, and its increasing prevalence
parallels the global rise in diabetes and obesity. It is characterised by fat accumulation in the …

The role of nutrition in non‐alcoholic fatty liver disease: pathophysiology and management

G Berná, M Romero‐Gomez - Liver International, 2020 - Wiley Online Library
A healthy diet together with physical activity could induce weight loss and control the
progression of non‐alcoholic fatty liver disease (NAFLD). However, the composition of diet …

The interplay between insulin resistance, inflammation, oxidative stress, base excision repair and metabolic syndrome in nonalcoholic fatty liver disease

S Ziolkowska, A Binienda, M Jabłkowski… - International journal of …, 2021 - mdpi.com
One of the most common chronic liver disorders, affecting mainly people in Western
countries, is nonalcoholic fatty liver disease (NAFLD). Unfortunately, its pathophysiological …

[HTML][HTML] Gut microbes in metabolic disturbances. Promising role for therapeutic manipulations?

P Portincasa, M Khalil, A Graziani, G Frühbeck… - European Journal of …, 2024 - Elsevier
The prevalence of overweight, obesity, type 2 diabetes, metabolic syndrome and steatotic
liver disease is rapidly increasing worldwide with a huge economic burden in terms of …

Towards precision medicine in non-alcoholic fatty liver disease

SM Francque - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) refers to the accumulation of lipid laden
vacuoles in hepatocytes, occurring in the context of visceral adiposity, insulin resistance and …

TRIM56 protects against nonalcoholic fatty liver disease by promoting the degradation of fatty acid synthase

S Xu, X Wu, S Wang, M Xu, T Fang… - The Journal of …, 2024 - Am Soc Clin Investig
Nonalcoholic fatty liver disease (NAFLD) encompasses a disease continuum from simple
steatosis to nonalcoholic steatohepatitis (NASH). However, there are currently no approved …

Towards an adiposity-related disease framework for the diagnosis and management of obesities

CM Perdomo, I Avilés-Olmos, D Dicker… - Reviews in Endocrine …, 2023 - Springer
Obesity is a complex disease that relapses frequently and associates with multiple
complications that comprise a worldwide health priority because of its rising prevalence and …

Non-alcoholic fatty liver disease as a canonical example of metabolic inflammatory-based liver disease showing a sex-specific prevalence: relevance of estrogen …

S Della Torre - Frontiers in endocrinology, 2020 - frontiersin.org
There is extensive evidence supporting the interplay between metabolism and immune
response, that have evolved in close relationship, sharing regulatory molecules and …