Nephrotoxicity is one of the most important side effects and therapeutical limitations of
aminoglycoside antibiotics, especially gentamicin. Despite rigorous patient monitoring …

Due to high relative blood flow the kidney is prone to drug-induced damage.
Aminoglycoside type antibiotic gentamicin is one of the leading cause of drug-induced …

Gentamicin is an aminoglycoside antibiotic widely used against infections by Gram-negative
microorganisms. Nephrotoxicity is the main limitation to its therapeutic efficacy. Gentamicin …

Drug-induced nephrotoxicity is a serious problem in patients with hospital-acquired acute
kidney injury (AKI). A new renal biomarker is needed because traditional markers are not …

Sulforaphane (SFN), an isothiocyanate naturally occurring in Cruciferae, induces
cytoprotection in several tissues. Its protective effect has been associated with its ability to …

Background Drug-induced kidney injury (DIKI) can be manifested with progressive chronic
kidney diseases or end-stage renal diseases. Understanding the molecular …

Gentamicin (GM) is an antibiotic belonging to an aminoglycoside family that might induce
nephrotoxicity in human and animal models via oxidative stress. Toll-like receptors (TLRs) …

Aim Gentamicin (GM) is one of the commonest causes of drug‐induced nephrotoxicity.
Moreover, oxidative stress plays an important role in gentamicin‐induced nephrotoxicity …

Emerging literature implicates acid sphingomyelinase in tumor sensitivity/resistance to
anticancer treatments. Gentamicin is a drug commonly used as an antimicrobial but its …

Umbilical cord mesenchymal stem cell-derived extracellular vesicles (UC-EVs) are valuable
in nanomedicine as natural nanocarriers, carrying information molecules from their parent …