Topical antimicrobial peptide formulations for wound healing: Current developments and future prospects

RK Thapa, DB Diep, HH Tønnesen - Acta biomaterialia, 2020 - Elsevier
Antimicrobial peptides (AMPs) are the natural antibiotics recognized for their potent
antibacterial and wound healing properties. Bare AMPs have limited activity following topical …

Advanced therapeutic dressings for effective wound healing—a review

J Boateng, O Catanzano - Journal of pharmaceutical sciences, 2015 - Elsevier
Advanced therapeutic dressings that take active part in wound healing to achieve rapid and
complete healing of chronic wounds is of current research interest. There is a desire for …

[HTML][HTML] Antimicrobial peptides–unleashing their therapeutic potential using nanotechnology

S Gera, E Kankuri, K Kogermann - Pharmacology & Therapeutics, 2022 - Elsevier
Antimicrobial peptides (AMPs) are potent, mostly cationic, and amphiphilic broad-spectrum
host defense antimicrobials that are produced by all organisms ranging from prokaryotes to …

[HTML][HTML] Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era

L Lin, J Chi, Y Yan, R Luo, X Feng, Y Zheng… - … Pharmaceutica Sinica B, 2021 - Elsevier
Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or
anticarcinogens that present a general killing mechanism through the physical disruption of …

Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action

TPT Cushnie, NH O'Driscoll, AJ Lamb - Cellular and molecular life …, 2016 - Springer
Efforts to reduce the global burden of bacterial disease and contend with escalating
bacterial resistance are spurring innovation in antibacterial drug and biocide development …

[HTML][HTML] Emollient treatment of atopic dermatitis: latest evidence and clinical considerations

KL Hon, JSC Kung, WGG Ng, TF Leung - Drugs in context, 2018 - ncbi.nlm.nih.gov
Aim To review current classes of emollients in the market, their clinical efficacy in atopic
dermatitis (AD) and considerations for choice of an emollient. Methods PubMed Clinical …

d-Amino acids in antimicrobial peptides: a potential approach to treat and combat antimicrobial resistance

S Kapil, V Sharma - Canadian journal of microbiology, 2021 - cdnsciencepub.com
Antimicrobial resistance is one of the leading challenges in the human healthcare segment.
Advances in antimicrobial resistance have triggered exploration of natural alternatives to …

Pexiganan in combination with nisin to control polymicrobial diabetic foot infections

D Gomes, R Santos, R S. Soares, S Reis, S Carvalho… - Antibiotics, 2020 - mdpi.com
Diabetic foot ulcers (DFUs) are major complications of Diabetes mellitus being responsible
for significant morbidity and mortality. DFUs frequently become chronically infected by a …

The role of natural antimicrobial peptides during infection and chronic inflammation

X Xia, L Cheng, S Zhang, L Wang, J Hu - Antonie Van Leeuwenhoek, 2018 - Springer
Natural antimicrobial peptides (AMPs), a family of small polypeptides that are produced by
constitutive or inducible expression in organisms, are integral components of the host innate …

Diabetic foot infections: Application of a nisin-biogel to complement the activity of conventional antibiotics and antiseptics against Staphylococcus aureus biofilms

R Santos, D Ruza, E Cunha, L Tavares, M Oliveira - PloS one, 2019 - journals.plos.org
Background Diabetic foot infections (DFIs) are a frequent complication of Diabetes mellitus
and a major cause of nontraumatic limb amputations. The Gram-positive bacterium …