Nano based-oncolytic viruses for cancer therapy

M Ajam-Hosseini, F Akhoondi, M Doroudian - Critical Reviews in Oncology …, 2023 - Elsevier
Oncolytic viruses (OV) are an attractive prospect due to their dual attack mechanism of direct
cell lysis and potentiation of an antitumor immune response. Various oncolytic viral vectors …

Exosomes as a drug delivery tool for cancer therapy: A new era for existing drugs and oncolytic viruses

Y Kakiuchi, S Kuroda, N Kanaya… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Exosomes are cell-derived nanovesicles involved in cell-to-cell
communications. These nanovesicles are generally considered to contain important carriers …

[HTML][HTML] Bacteria-based immunotherapy for cancer: a systematic review of preclinical studies

M Zhou, Y Tang, W Xu, X Hao, Y Li, S Huang… - Frontiers in …, 2023 - frontiersin.org
Immunotherapy has been emerging as a powerful strategy for cancer management.
Recently, accumulating evidence has demonstrated that bacteria-based immunotherapy …

[HTML][HTML] Oncolytic viral vectors in the era of diversified cancer therapy: From preclinical to clinical

C Tang, L Li, T Mo, J Na, Z Qian, D Fan, X Sun… - Clinical and …, 2022 - Springer
With the in-depth research and wide application of immunotherapy recently, new therapies
based on oncolytic viruses are expected to create new prospects for cancer treatment via …

Cancer therapy with the viral and bacterial pathogens: The past enemies can be considered the present allies

N Kiaheyrati, A Babaei, R Ranji, E Bahadoran, S Taheri… - Life Sciences, 2024 - Elsevier
Cancer continues to be one of the leading causes of mortality worldwide despite significant
advancements in cancer treatment. Many difficulties have arisen as a result of the …

[HTML][HTML] Hacking the immune response to solid tumors: harnessing the anti-cancer capacities of oncolytic bacteria

JM Roe, K Seely, CJ Bussard, E Eischen Martin… - Pharmaceutics, 2023 - mdpi.com
Oncolytic bacteria are a classification of bacteria with a natural ability to specifically target
solid tumors and, in the process, stimulate a potent immune response. Currently, these …

[HTML][HTML] Nanotechnology for pediatric retinoblastoma therapy

E Russo, A Spallarossa, B Tasso, C Villa, C Brullo - Pharmaceuticals, 2022 - mdpi.com
Retinoblastoma is a rare, sometimes hereditary, pediatric cancer. In high-income countries
this disease has a survival rate approaching 100%, while in low-and middle-income …

[HTML][HTML] An intravenous pancreatic cancer therapeutic: Characterization of CRISPR/Cas9n-modified Clostridium novyi-Non Toxic

KM Dailey, JM Small, JE Pullan, S Winfree, KE Vance… - Plos one, 2023 - journals.plos.org
Clostridium novyi has demonstrated selective efficacy against solid tumors largely due to the
microenvironment contained within dense tumor cores. The core of a solid tumor is typically …

Testosterone therapy and prostate cancer: incorporating low-level evidence into practical recommendations

A Morales, DR Siemens - Urologic Clinics, 2022 - urologic.theclinics.com
In men's health 2 fields share the characteristics of being both controversial and involving
several medical disciplines: testosterone deficiency syndrome (TDS) and prostate cancer …

Nanomaterial‐assisted oncolytic bacteria in solid tumor diagnosis and therapeutics

X Zeng, Q Chen, T Chen - Bioengineering & Translational …, 2024 - Wiley Online Library
Cancer presents a formidable challenge in modern medicine due to the intratumoral
heterogeneity and the dynamic microenvironmental niche. Natural or genetically engineered …