[图书][B] Epilepsy: a public health imperative

World Health Organization - 2019 - apps.who.int
Epilepsy is a brain disease characterized by abnormal electrical activity causing seizures or
unusual behaviour, sensations and sometimes loss of awareness. It carries neurological …

Environmental enrichment as an experience-dependent modulator of social plasticity and cognition

C Gubert, AJ Hannan - Brain Research, 2019 - Elsevier
Social plasticity is the ability to adaptively change the expression of social behaviour
according to experience, allowing animals to optimize their social relationships in the …

Comorbidity and childhood epilepsy: a nationwide registry study

KM Aaberg, IJ Bakken, MI Lossius, C Lund Søraas… - …, 2016 - publications.aap.org
METHODS: Data were obtained from the Norwegian Patient Registry, which is an
administrative database recording International Classification of Diseases, 10th Revision …

Early life epilepsies are a comorbidity of developmental brain disorders

AT Berg, D Tarquinio, S Koh - Seminars in pediatric neurology, 2017 - Elsevier
Early-life epilepsies are a series of disorders frequently accompanied by a broad range of
morbidities that include cognitive, behavioral, neuromuscular, and sleep disturbances; …

Continuing burden of refractory epilepsy

MT Janson, JL Bainbridge - Annals of Pharmacotherapy, 2021 - journals.sagepub.com
Epilepsy is one of the most common neurological diseases, and uncontrolled seizures
remain a significant problem for one-third of patients with epilepsy on drug therapy. Ongoing …

Efficacy and tolerability of adjunctive lacosamide in pediatric patients with focal seizures

V Farkas, B Steinborn, JR Flamini, Y Zhang, N Yuen… - Neurology, 2019 - AAN Enterprises
Objective To evaluate efficacy and tolerability of adjunctive lacosamide in children and
adolescents with uncontrolled focal (partial-onset) seizures. Methods In this double-blind …

Dynamic miRNA changes during the process of epileptogenesis in an infantile and adult-onset model

P Bencurova, J Baloun, J Hynst, J Oppelt, H Kubova… - Scientific Reports, 2021 - nature.com
Temporal lobe epilepsy (TLE) is the most common epilepsy type. TLE onset in infancy
aggravates features like severity, drug responsiveness, or development of comorbidities …

Everolimus is better than rapamycin in attenuating neuroinflammation in kainic acid-induced seizures

MT Yang, YC Lin, WH Ho, CL Liu, WT Lee - Journal of Neuroinflammation, 2017 - Springer
Background Microglia is responsible for neuroinflammation, which may aggravate brain
injury in diseases like epilepsy. Mammalian target of rapamycin (mTOR) kinase is related to …

Risk factors for poor bone health in primary mitochondrial disease

SS Gandhi, C Muraresku, EM McCormick… - Journal of inherited …, 2017 - Springer
Introduction Primary mitochondrial disease is caused by either mitochondrial or nuclear
DNA mutations that impact the function of the mitochondrial respiratory chain. Individuals …

Prospective evaluation of ghrelin and des-acyl ghrelin plasma levels in children with newly diagnosed epilepsy: evidence for reduced ghrelin-to-des-acyl ghrelin ratio …

AM Costa, T Lo Barco, E Spezia, V Conti, L Roli… - Journal of Personalized …, 2022 - mdpi.com
Children with epilepsy and identified as responders to antiseizure medications (ASMs) were
found to present markedly higher ghrelin plasma levels when compared to drug-resistant …