Stereoselective synthesis and applications of spirocyclic oxindoles

AJ Boddy, JA Bull - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
The development of novel synthetic strategies to form new chemical entities in a
stereoselective manner is an ongoing significant objective in organic and medicinal …

Chitosan nanoparticle encapsulation of antibacterial essential oils

A Negi, KK Kesari - Micromachines, 2022 - mdpi.com
Chitosan is the most suitable encapsulation polymer because of its natural abundance,
biodegradability, and surface functional groups in the form of free NH2 groups. The …

Enzymatic kinetic resolution of bulky spiro-epoxyoxindoles via halohydrin dehalogenase-catalyzed enantio-and regioselective azidolysis

FR Zhang, NW Wan, JM Ma, BD Cui, WY Han… - ACS …, 2021 - ACS Publications
It is significant to expand enzymatic catalysis in order to develop efficient strategies for the
synthesis of valued molecules. Herein, an efficient enzymatic process involving the catalytic …

Weinreb amides as privileged acylating agents for accessing α-substituted ketones

R Senatore, L Ielo, S Monticelli, L Castoldi, V Pace - Synthesis, 2019 - thieme-connect.com
The acylation of α-substituted carbanion-type reagents (MCR 1 R 2 X; X= halogen, OR, SR,
NR 3 R 4, SeR, etc.) with Weinreb amides constitutes a highly versatile and flexible …

Epoxides: Small rings to play with under asymmetric organocatalysis

S Meninno, A Lattanzi - ACS Organic & Inorganic Au, 2022 - ACS Publications
Optically pure epoxides are recognized as highly valuable products and key intermediates,
useful in different areas from pharmaceutical and agrochemical industries to natural product …

Advances in the Synthesis of Benzo‐Fused Spiro Nitrogen Heterocycles: New approaches and modification of old strategies

RR Gataullin - Helvetica Chimica Acta, 2020 - Wiley Online Library
The review covers the results of studies published in the literature on the synthesis of spiro‐
linked heterocycles of the indole, quinoline, benzoxazine, benzothiazine …

Feedback inhibition in chemical catalysis leads the dynamic kinetic to kinetic resolution in C3-indolylation of spiro-epoxyoxindoles

S Hajra, S Roy - Organic letters, 2020 - ACS Publications
The first feedback inhibition, similar to enzyme catalysis, in the Co (III) salen-catalyzed
asymmetric ring-opening reaction of N-free spiro-epoxyoxyindole has been discovered …

Carbenoid-Mediated Homologation Tactics for Assembling (Fluorinated) Epoxides and Aziridines

L Ielo, V Pillari, M Miele, D Castiglione, V Pace - Synlett, 2021 - thieme-connect.com
Homologation strategies provide highly versatile tools in organic synthesis for the
introduction of a CH 2 group into a given carbon skeleton. The operation can result in …

Chemoselective homologative preparation of trisubstituted alkenyl halides from carbonyls and carbenoids

M Miele, D Castiglione, W Holzer, L Castoldi… - Chemical …, 2025 - pubs.rsc.org
The chemoselective synthesis of trisubstituted alkenyl halides (Cl, Br, F, I) starting from
ketones and aldehydes and lithium halocarbenoids is reported. Upon forming the …

[PDF][PDF] Chitosan Nanoparticle Encapsulation of Antibacterial Essential Oils. Micromachines 2022, 13, 1265

A Negi, KK Kesari - 2022 - academia.edu
Chitosan is the most suitable encapsulation polymer because of its natural abundance,
biodegradability, and surface functional groups in the form of free NH2 groups. The …