Mammalian sperm must undergo a series of biochemical and physiological modifications,
collectively called capacitation, in the female reproductive tract prior to the acrosome …

Fertilization is the process by which male and female haploid gametes (sperm and egg)
unite to produce a genetically distinct individual. In mammals, fertilization involves a number …

Background Male infertility is a major problem for mammalian reproduction. However,
molecular details including the underlying mechanisms of male fertility are still not known. A …

Fertility plays a key role in the success of calf production, but there is evidence that
reproductive efficiency in beef cattle has decreased during the past half-century worldwide …

In all mammalian species studied so far, sperm capacitation correlates with an increase in
protein tyrosine (Tyr) phosphorylation mediated by a bicarbonate-dependent cAMP/protein …

Nitric oxide (NO) enhances human sperm motility and capacitation associated with
increased protein phosphorylation. NO activates soluble guanylyl cyclase, but can also …

Proteomic profiling of the mouse spermatozoon has generated a unique and valuable
inventory of candidates that can be mined for potential contraceptive targets and to further …

The spermatozoon is an accessible cell which can be easily purified and therefore it is
particularly well suited for proteomic analysis. It is also an extremely differentiated cell with …

The conventional approach to evaluation of stallion semen dates back several decades, and
includes evaluation of spermatozoal concentration, semen volume, spermatozoon …

Following the discovery of mammalian sperm capacitation and its fundamental importance
for the acquisition of fertilizing potential, it has gradually become possible to identify some …