Treatment approaches to moderate to severe psoriasis

P Gisondi, M Del Giglio, G Girolomoni - International journal of molecular …, 2017 - mdpi.com
Psoriasis is a common disease, which has a considerable impact on patients and the health
care system. Treatment approaches to the disease may be various because some issues …

Risk of tuberculosis reactivation with interleukin (IL)‐17 and IL‐23 inhibitors in psoriasis–time for a paradigm change

M Nogueira, RB Warren, T Torres - Journal of the European …, 2021 - Wiley Online Library
Tuberculosis is an infectious disease with a major global impact, ranked in the top 10
mortality causes worldwide. In an immunocompetent individual, the host defence …

EuroGuiDerm Guideline on the systemic treatment of Psoriasis vulgaris–Part 1: treatment and monitoring recommendations

A Nast, C Smith, PI Spuls, G Avila Valle… - Journal of the …, 2020 - Wiley Online Library
This evidence‐and consensus‐based guideline on the treatment of psoriasis vulgaris was
developed following the EuroGuiDerm Guideline and Consensus Statement Development …

Hyaluronic acid-based dissolving microneedle patch loaded with methotrexate for improved treatment of psoriasis

H Du, P Liu, J Zhu, J Lan, Y Li, L Zhang… - … applied materials & …, 2019 - ACS Publications
Methotrexate (MTX) is one of the first-line treatments for moderate to severe psoriasis, while
the side effects caused by injection and oral administration of MTX greatly restrict its clinical …

Immune checkpoint-mediated psoriasis: A multicenter European study of 115 patients from the European Network for Cutaneous Adverse Event to Oncologic Drugs …

V Nikolaou, V Sibaud, D Fattore, P Sollena… - Journal of the American …, 2021 - Elsevier
Background Immune checkpoint inhibitor (ICI)–mediated psoriasis poses significant
diagnostic and therapeutic challenges. Objective To report data on ICI-mediated psoriasis …

Efficacy of tildrakizumab for the treatment of difficult-to-treat areas: scalp, nail, palmoplantar and genital psoriasis

M Galluzzo, M Talamonti, A Cioni, V Maffei… - Journal of Clinical …, 2022 - mdpi.com
Tildrakizumab, an IL-23 inhibitor, is effective and safe for the improvement of moderate-to-
severe chronic plaque psoriasis. However, little evidence is available on the use of this …

Latest advances for the treatment of chronic plaque psoriasis with biologics and oral small molecules

F Bellinato, P Gisondi, G Girolomoni - Biologics: Targets and …, 2021 - Taylor & Francis
Psoriasis is a common immune-mediated chronic skin disease. Disease severity is
influenced by several factors including the extent and localization of skin lesions, severity of …

Use of guselkumab for the treatment of moderate-to-severe plaque psoriasis: a 1 year real-life study

M Galluzzo, L Tofani, P Lombardo… - Journal of Clinical …, 2020 - mdpi.com
Little information is available from real-life studies evaluating the efficacy of guselkumab in
moderate-to-severe psoriasis. In this real-life study, we retrospectively examined a database …

Treat-to-target approach for the management of patients with moderate-to-severe plaque psoriasis: consensus recommendations

P Gisondi, M Talamonti, A Chiricozzi, S Piaserico… - Dermatology and …, 2021 - Springer
Introduction Treat-to-target strategies are used in several chronic diseases to improve
outcomes. Treatment goals have also been suggested for psoriasis, but there is currently no …

COVID‐19 knowledge prevents biologics discontinuation: data from an Italian multicenter survey during RED‐ZONE declaration

NL Bragazzi, M Riccò, A Pacifico… - Dermatologic …, 2020 - Wiley Online Library
SARS‐CoV‐2 become pandemics and there is still a dearth of data about its the potentially
among dermatological patients under biologics. We aimed to assess health literacy, disease …