Byproducts of normal mitochondrial metabolism and homeostasis include the buildup of
potentially damaging levels of reactive oxygen species (ROS), Ca2+, etc., which must be …

Mitochondrial dysfunction has gained recognition as a contributing factor in many diseases.
The kidney is a kind of organ with high energy demand, rich in mitochondria. As such …

Phenoptosis is the death of an organism programmed by its genome. Numerous examples
of phenoptosis are described in prokaryotes, unicellular eukaryotes, and all kingdoms of …

Cisplatin, carboplatin and oxaliplatin represent the backbone of platinum therapy for several
malignancies including head and neck, lung, colorectal, ovarian, breast, and genitourinary …

Purpose Numerous studies have linked particulate matter2. 5 (PM2. 5) to ocular surface
diseases, but few studies have been conducted on the biological effect of PM2. 5 on the …

The recent revival of old theories and setting them on modern scientific rails to a large extent
are also relevant to mitochondrial science. Given the widespread belief that mitochondria …

Abstract (i) In 2015-2017 we compared possible reasons for longevity of two mammalian
highly social species, ie naked mole rats and humans. We proposed that in both cases …

Abstract MitoTEMPO (MT) and Visomitin (SKQ1) are regareded as mitochondria-targeted
antioxidants, which inhibit production of mitochondrial reactive oxygen species (ROS) …

Noise exposure causes noise-induced hearing loss (NIHL). NIHL exhibits loss of inner ear
sensory hair cells and is often irreparable. Although oxidative stress is involved in hearing …

Objectives: We investigated whether preexisting kidney function determines if ICU patients
may benefit from increased (2.0 g/kg/d) protein intake. Design: Post hoc, hypothesis …