Local treatment of breast cancer liver metastasis

R Bale, D Putzer, P Schullian - Cancers, 2019 - mdpi.com
Breast cancer represents a leading cause of death worldwide. Despite the advances in
systemic therapies, the prognosis for patients with breast cancer liver metastasis (BCLM) …

The FUS/circEZH2/KLF5/feedback loop contributes to CXCR4-induced liver metastasis of breast cancer by enhancing epithelial-mesenchymal transition

P Liu, Z Wang, X Ou, P Wu, Y Zhang, S Wu, X Xiao… - Molecular cancer, 2022 - Springer
Background Metastasis of breast cancer have caused the majority of cancer-related death
worldwide. The circRNAs are associated with tumorigenesis and metastasis in breast cancer …

Cryoablation and immunotherapy: an overview of evidence on its synergy

BM Aarts, EG Klompenhouwer, SL Rice, F Imani… - Insights into …, 2019 - Springer
Cancer cells can escape the immune system by different mechanisms. The evasion of
cancer cells from immune surveillance is prevented by immune checkpoint inhibitors …

The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin

Z Wang, L Yang, P Wu, X Li, Y Tang, X Ou, Y Zhang… - Molecular cancer, 2022 - Springer
Background Metastasis causes the majority of cancer-related deaths worldwide. Increasing
studies have revealed that circRNAs are associated with the carcinogenesis and metastasis …

Albumin nanoparticle containing a PI3Kγ inhibitor and paclitaxel in combination with α-PD1 induces tumor remission of breast cancer in mice

Y Song, L Bugada, R Li, H Hu, L Zhang, C Li… - Science translational …, 2022 - science.org
Immunomodulators that remodel the tumor immunosuppressive microenvironment have
been combined with anti–programmed death 1 (α-PD1) or anti–programmed death ligand 1 …

Comparison of patterns and prognosis among distant metastatic breast cancer patients by age groups: a SEER population-based analysis

MT Chen, HF Sun, Y Zhao, WY Fu, LP Yang, SP Gao… - Scientific reports, 2017 - nature.com
To investigate the effects of age at diagnosis on metastatic breast cancer and patients'
prognosis, we collected patient data from the Surveillance, Epidemiology, and End Results …

Targeting the TIGIT-PVR immune checkpoint axis as novel therapeutic option in breast cancer

H Stamm, L Oliveira-Ferrer, EM Grossjohann… - …, 2019 - Taylor & Francis
Immune checkpoints are intensively investigated as targets in cancer therapy. T-cell
immunoreceptor with immunoglobulin (Ig) and ITIM domains (TIGIT) and its ligand poliovirus …

Engineering an active immunotherapy for personalized cancer treatment and prevention of recurrence

K Wu, F Lyu, SY Wu, S Sharma, RP Deshpande… - Science …, 2023 - science.org
Breast cancer has been shown to be resistant to immunotherapies. To overcome this
challenge, we developed an active immunotherapy for personalized treatment based on a …

Clinical relevancy of circulating tumor cells in breast cancer: epithelial or mesenchymal characteristics, single cells or clusters?

I Fridrichova, L Kalinkova, S Ciernikova - International Journal of …, 2022 - mdpi.com
Metastatic breast cancer (MBC) is typically an incurable disease with high mortality rates;
thus, early identification of metastatic features and disease recurrence through precise …

An ontology-guided semantic data integration framework to support integrative data analysis of cancer survival

H Zhang, Y Guo, Q Li, TJ George, E Shenkman… - BMC medical informatics …, 2018 - Springer
Background Cancer is the second leading cause of death in the United States, exceeded
only by heart disease. Extant cancer survival analyses have primarily focused on individual …