DNA damage response and repair in colorectal cancer: Defects, regulation and therapeutic implications

M Mirza-Aghazadeh-Attari, SG Darband, M Kaviani… - DNA repair, 2018 - Elsevier
DNA damage response, a key factor involved in maintaining genome integrity and stability,
consists of several kinase-dependent signaling pathways, which sense and transduce DNA …

Long non-coding RNA SNHG17 is an unfavourable prognostic factor and promotes cell proliferation by epigenetically silencing P57 in colorectal cancer

Z Ma, S Gu, M Song, C Yan, B Hui, H Ji, J Wang… - Molecular …, 2017 - pubs.rsc.org
Recently, substantial evidence has demonstrated that long non-coding RNAs (lncRNAs)
play critical roles in multiple cancers including colorectal cancer (CRC). Utilizing publicly …

Cold atmospheric plasma treatment inhibits growth in colorectal cancer cells

C Schneider, S Arndt, JL Zimmermann, Y Li… - Biological …, 2018 - degruyter.com
Plasma oncology is a relatively new field of research. Recent developments have indicated
that cold atmospheric plasma (CAP) technology is an interesting new therapeutic approach …

[HTML][HTML] Long non-coding RNA SH3PXD2A-AS1 promotes cell progression partly through epigenetic silencing P57 and KLF2 in colorectal cancer

Z Ma, P Peng, J Zhou, B Hui, H Ji, J Wang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Colorectal cancer (CRC) is one of the most commonly diagnosed
malignancies worldwide. Current evidence has revealed the key roles of long non-coding …

p16 Expression in Multinucleated Stromal Cells of Fibroepithelial Polyps of the Anus (FEPA): A Comprehensive Review and Our Experience

M Gulinac, T Velikova, L Tomov, D Dikov - Gastroenterology Insights, 2024 - mdpi.com
Fibroepithelial polyps of the anus (FEPA) are a common benign polypoid proliferation of the
stroma covered by squamous epithelium. They are also an often-overlooked part of …

Prognostic and clinicopathological value of p16 protein aberrant expression in colorectal cancer: A PRISMA-compliant Meta-analysis

N Zhou, Q Gu - Medicine, 2018 - journals.lww.com
Purpose: Several studies have examined the potential role of p16 protein expression as a
diagnostic and prognostic biomarker in various cancers. However, it remains unclear …

[HTML][HTML] Association of KRAS Mutation and Gene Pathways in Colorectal Carcinoma: A Transcriptome- and Methylome-Wide Study and Potential Implications for …

F Jasmine, A Almazan, Y Khamkevych… - International Journal of …, 2024 - mdpi.com
Kirsten Rat Sarcoma (KRAS) is the most commonly mutated oncogene in colorectal
carcinoma (CRC). We have previously reported the interactions between microsatellite …

Novel genomic alteration in superficial esophageal squamous cell neoplasms in non-smoker non-drinker females

Y Onozato, Y Sasaki, Y Abe, H Sato, M Yagi… - Scientific Reports, 2021 - nature.com
Alcohol consumption and smoking pose a significant risk for esophageal squamous cell
neoplasia (ESCN) development in males; however, ESCN is often diagnosed in non …

[PDF][PDF] Differences in Clinicopathological Features, P16Ink4a and P57KIP2 Immunohistochemical Expressions, and Survival Between Colorectal Carcinoma in …

FAA Elkhamisy, EA Aboelkomsan, MF Abd AlRahman - Cureus, 2024 - cureus.com
Background One unique criterion of colorectal carcinoma (CRC) is the different locations
within the colorectum. Different CRC sidedness/locations could have distinct criteria …

Expression of p16 Marker in Colorectal Cancer and its Association with Clinicopathologic Parameters in Patients with Colectomy Surgery

B Balali, P Kheradmand, N Ranjbari… - Journal of Applied …, 2022 - biotechrep.ir
Introduction: Colorectal Cancer (CRC) is a genetic disease with complex and diverse
pathways. The p16 is a tumor-inhibiting gene that acts as a regulator of the cell cycle …