Yeast glucan particles: An express train for oral targeted drug delivery systems

F Yang, S Shang, M Qi, Y Xiang, L Wang… - International Journal of …, 2023 - Elsevier
As an emerging drug delivery vehicle, yeast glucan particles (YGPs) derived from yeast cells
could be specifically taken up by macrophages. Therefore, these vehicles could rely on the …

[HTML][HTML] Investigation of the influence of anti-solvent precipitation parameters on the physical stability of amorphous solids

Z Li, Z Gong, B Zhang, A Nawaz - Molecules, 2024 - mdpi.com
Amorphous solids exhibit enhanced solubility and dissolution rates relative to their
crystalline counterparts. However, attaining optimal bioavailability presents a challenge …

Magnetic Yeast Glucan Particles for Antibody-Free Separation of Viable Macrophages from Drosophila melanogaster

G Krejčová, I Saloň, V Klimša… - ACS Biomaterials …, 2023 - ACS Publications
Currently available methods for cell separation are generally based on fluorescent labeling
using either endogenously expressed fluorescent markers or the binding of antibodies or …

Ivacaftor pharmacokinetics and lymphatic transport after enteral administration in rats

J Pozniak, P Ryšánek, D Smrčka, P Kozlík… - Frontiers in …, 2024 - frontiersin.org
Background: Ivacaftor is a modern drug used in the treatment of cystic fibrosis. It is highly
lipophilic and exhibits a strong positive food effect. These characteristics can be potentially …

Dispersive micro-solid phase extraction based on two MOFs as highly effective adsorbents for analysis of nilotinib in plasma and wastewater

A Takhvar, S Akbari, E Souri, R Ahmadkhaniha… - DARU Journal of …, 2024 - Springer
Background Nilotinib (NIL) is a prescription medication employed in the treatment of specific
types of leukemia, namely chronic myelogenous leukemia (CML). The determination of NIL …

Inhibition of mevalonate pathway by macrophage‐specific delivery of atorvastatin prevents their pro‐inflammatory polarisation

G Krejčová, G Ruphuy, P Šalamúnová… - Insect Molecular …, 2024 - Wiley Online Library
Adjustment of the cellular metabolism of pro‐inflammatory macrophages is essential for their
bactericidal function; however, it underlies the development of many human diseases if …