Betaine chemistry, roles, and potential use in liver disease

CR Day, SA Kempson - Biochimica et Biophysica Acta (BBA)-General …, 2016 - Elsevier
Background Betaine is the trimethyl derivative of glycine and is normally present in human
plasma due to dietary intake and endogenous synthesis in liver and kidney. Betaine is …

Increased urinary osmolyte excretion indicates chronic kidney disease severity and progression rate

RB Gil, A Ortiz, MD Sanchez-Niño… - Nephrology dialysis …, 2018 - academic.oup.com
Background Chronic kidney disease (CKD) is a recognized global health problem. While
some CKD patients remain stable after initial diagnosis, others can rapidly progress towards …