Global epidemiology of systemic lupus erythematosus

MRW Barber, C Drenkard, T Falasinnu, A Hoi… - Nature Reviews …, 2021 - nature.com
Systemic lupus erythematosus (SLE) is an autoimmune disease with protean manifestations
that predominantly affects young women. Certain ethnic groups are more vulnerable than …

Long-term outcomes in systemic lupus erythematosus: trends over time and major contributors

L Arnaud, MG Tektonidou - Rheumatology, 2020 - academic.oup.com
SLE is a chronic autoimmune rheumatic disorder of high heterogeneity in clinical
presentation, treatment response and prognosis. Long-term outcomes in SLE have been …

Global epidemiology of systemic lupus erythematosus: a comprehensive systematic analysis and modelling study

J Tian, D Zhang, X Yao, Y Huang, Q Lu - Annals of the rheumatic …, 2023 - ard.bmj.com
Objectives To quantify global, regional and country-specific estimates of epidemiology of
systemic lupus erythematosus (SLE). Methods Four databases were systematically …

Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 3 trial (SLE-BRAVE-II)

M Petri, IN Bruce, T Dörner, Y Tanaka, EF Morand… - The Lancet, 2023 - thelancet.com
Background Baricitinib is an oral selective inhibitor of Janus kinase 1 and 2 approved for the
treatment of rheumatoid arthritis, atopic dermatitis, and alopecia areata. In a 24-week phase …

Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 3 trial (SLE-BRAVE-I)

EF Morand, EM Vital, M Petri, R van Vollenhoven… - The Lancet, 2023 - thelancet.com
Background Baricitinib is an oral selective inhibitor of Janus kinase 1 and 2 approved for the
treatment of rheumatoid arthritis, atopic dermatitis, and alopecia areata. In a 24-week phase …

Effectiveness of belimumab after rituximab in systemic lupus erythematosus: a randomized controlled trial

M Shipa, A Embleton-Thirsk, M Parvaz… - Annals of internal …, 2021 - acpjournals.org
Background: B-cell depletion with rituximab is commonly used for patients with systemic
lupus erythematosus (SLE) that is refractory to conventional therapy, but it yields variable …

New therapeutic strategies in systemic lupus erythematosus management

M Gatto, M Zen, L Iaccarino, A Doria - Nature Reviews Rheumatology, 2019 - nature.com
The current treatment approach for systemic lupus erythematosus (SLE), as outlined in the
recommendations by international medical associations including EULAR and the ACR, is …

The pathogenesis of systemic lupus erythematosus: harnessing big data to understand the molecular basis of lupus

MD Catalina, KA Owen, AC Labonte, AC Grammer… - Journal of …, 2020 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease that causes
damage to multiple organ systems. Despite decades of research and available murine …

Mortality in systemic lupus erythematosus: causes, predictors and interventions

V Ocampo-Piraquive, I Nieto-Aristizábal… - Expert review of …, 2018 - Taylor & Francis
Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease
characterized by organ damage, flare-remission pattern, and increased mortality when …

Update on the epidemiology, risk factors, and disease outcomes of systemic lupus erythematosus

I Gergianaki, A Bortoluzzi, G Bertsias - Best Practice & Research Clinical …, 2018 - Elsevier
Obtaining an updated view of the epidemiology, risk factors, and prognosis of systemic lupus
erythematosus (SLE) is pivotal to our understanding of the disease burden. Recent …