In 2007, 1179 papers were published that involved the application of optical biosensors.
Reported developments in instrument hardware, assay design, and immobilization …

Enzymes of the UDP-glucuronosyltransferase (UGT) superfamily contribute to the
elimination of drugs from almost all therapeutic classes. Awareness of the importance of …

The direct interaction of drugs with the cell membrane is often neglected when drug effects
are studied. Systematic investigations are hindered by the complexity of the natural …

The influenza A virus contains a proton-selective ion channel (M2) that is the target of the
adamantane family of drug inhibitors. Two recently published studies relating to …

Here we report the use of counter-propagating second harmonic generation (SHG) to image
the interactions between the local anesthetic tetracaine and a multicomponent planar …

Drug‐induced phospholipidosis (PLD) is a lysosomal storage disorder characterized by the
accumulation of phospholipids within the lysosome. This adverse drug effect can occur in …

We have synthesized two series of bile acid tamoxifen conjugates using three bile acids
lithocholic acid (LCA), deoxycholic acid (DCA), and cholic acid (CA). These bile acid …

Theonellamides (TNMs) are members of a distinctive family of antifungal and cytotoxic
bicyclic dodecapeptides isolated from the marine sponge Theonella sp. Recently, it has …

Sphingolipids are not only structural components of biological membranes, but also play an
important role in cellular signalling and, thus, are involved in cell proliferation and …

The objective of this study was to study the effect of four different bile salts, cholate (C),
deoxycholate (DC), taurocholate (TC), monoketocholate (MKC), on the membrane binding of …