Phase II metabolic enzymes are a battery of critical proteins that detoxify xenobiotics by
increasing their hydrophilicity and enhancing their disposal. These enzymes have long been …

Exercise training represents a behavioral approach for safely managing many of the
functional, symptomatic, and quality of life consequences of multiple sclerosis (MS). This …

Cognitive decline is common in multiple sclerosis and strongly affects overall quality of life.
Despite the identification of cross-sectional MRI correlates of cognitive impairment …

Changes in gene expression that occur across the central nervous system (CNS) during
neurological diseases do not address the heterogeneity of cell types from one CNS region to …

Objective To examine the validity of the timed Up and Go (TUG) test as a measure of
functional mobility in persons with multiple sclerosis (MS) by using a comprehensive …

An international expert consensus committee recently recommended a brief battery of tests
for cognitive evaluation in multiple sclerosis. The Brief International Cognitive Assessment …

A pressing need exists to disentangle age-related changes from pathologic
neurodegeneration. This study aims to characterize the spatial pattern and age-related …

Multiple sclerosis (MS) is a chronic, progressive disease of the central nervous system that is
characterised by inflammatory damage to the myelin sheath. Though often neglected …

Objective: This study investigates whether changes in functional connectivity, diffusivity, and
volume of the thalamus can explain different severities of cognitive impairment in multiple …

Background: Exercise may have beneficial effects on both well-being and walking ability in
multiple sclerosis (MS). Exercise is shown to be neuroprotective in rodents and may also …