Theoretical and computational studies of dendrimers as delivery vectors
Y Ma - Chemical Society Reviews, 2013 - pubs.rsc.org
It is a great challenge for nanomedicine to develop novel dendrimers with maximum
therapeutic potential and minimum side-effects for drug and gene delivery. As delivery …
therapeutic potential and minimum side-effects for drug and gene delivery. As delivery …
Neutron scattering in the biological sciences: progress and prospects
The scattering of neutrons can be used to provide information on the structure and dynamics
of biological systems on multiple length and time scales. Pursuant to a National Science …
of biological systems on multiple length and time scales. Pursuant to a National Science …
Tkatchenko-Scheffler van der Waals correction method with and without self-consistent screening applied to solids
The method proposed by Tkatchenko and Scheffler [Phys. Rev. Lett. 102, 073005 (2009)
PRLTAO 0031-9007 10.1103/PhysRevLett. 102.073005] to correct density functional …
PRLTAO 0031-9007 10.1103/PhysRevLett. 102.073005] to correct density functional …
Probing the inner local density of complex macromolecules by pyrene excimer formation
H Little, S Patel, J Duhamel - Physical Chemistry Chemical Physics, 2023 - pubs.rsc.org
The direct relationship existing between the average rate constant< k> for pyrene excimer
formation and the local concentration [Py] loc of ground-state pyrenyl labels covalently …
formation and the local concentration [Py] loc of ground-state pyrenyl labels covalently …
Functionalized branched polymers: promising immunomodulatory tools for the treatment of cancer and immune disorders
Well-defined synthetic branched nanostructures form an emerging subclass of
macromolecular structures whose 3D structure and multivalency offer unique opportunities …
macromolecular structures whose 3D structure and multivalency offer unique opportunities …
Effects of PEGylation on the size and internal structure of dendrimers: self-penetration of long PEG chains into the dendrimer core
G4 PAMAM dendrimers grafted with poly (ethylene glycol)(PEG) of different sizes (M w= 550
and 5000) and grafting densities (12− 94% of surface terminals) were simulated using the …
and 5000) and grafting densities (12− 94% of surface terminals) were simulated using the …
Understanding effects of PAMAM dendrimer size and surface chemistry on serum protein binding with discrete molecular dynamics simulations
Polyamidoamine (PAMAM) dendrimers, a class of polymeric nanoparticles (NPs) with highly
controllable sizes and surface chemistry, are promising candidates for many biomedical …
controllable sizes and surface chemistry, are promising candidates for many biomedical …
Poly (amidoamine)‐based dendrimer/siRNA complexation studied by computer simulations: effects of pH and generation on dendrimer structure and siRNA Binding
In this work we report, compare and discuss the results obtained from fully atomistic
molecular dynamics simulations of generations 4, 5, and 6 of PAMAM‐based dendrimers …
molecular dynamics simulations of generations 4, 5, and 6 of PAMAM‐based dendrimers …
Quantitative analysis of generation and branch defects in G5 poly (amidoamine) dendrimer
MA van Dongen, A Desai, BG Orr, JR Baker Jr… - Polymer, 2013 - Elsevier
Although methods have been developed to synthesize and isolate generation 5 (G5)
PAMAM dendrimers containing precise numbers of ligands per polymer particle, the …
PAMAM dendrimers containing precise numbers of ligands per polymer particle, the …
Intramacromolecular Conformational Changes in Low Generation PAMAM Dendrimers Probed by Pyrene Excimer Formation
Pyrene excimer formation (PEF) was used to probe the intramacromolecular conformational
change experienced by low generation pyrene-labeled PAMAM dendrimers referred to as …
change experienced by low generation pyrene-labeled PAMAM dendrimers referred to as …