Critical analysis of antibacterial agents in clinical development
U Theuretzbacher, K Bush, S Harbarth… - Nature Reviews …, 2020 - nature.com
The antibacterial agents currently in clinical development are predominantly derivatives of
well-established antibiotic classes and were selected to address the class-specific …
well-established antibiotic classes and were selected to address the class-specific …
Monitoring of drug resistance towards reducing the toxicity of pharmaceutical compounds: Past, present and future
Drug resistance is worldwide health care crisis which decrease drug efficacy and
developing toxicities. Effective resistance detection techniques could alleviate treatment cost …
developing toxicities. Effective resistance detection techniques could alleviate treatment cost …
Emergence of mcr-9.1 in Extended-Spectrum-β-Lactamase-Producing Clinical Enterobacteriaceae in Pretoria, South Africa: Global Evolutionary Phylogenomics …
J Osei Sekyere, NE Maningi, L Modipane, NM Mbelle - MSystems, 2020 - Am Soc Microbiol
ABSTRACT Extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceae are
critical-priority pathogens that cause substantial fatalities. With the emergence of mobile mcr …
critical-priority pathogens that cause substantial fatalities. With the emergence of mobile mcr …
[HTML][HTML] Bioinformatics analysis reveals lipid metabolism may play an important role in the SiO2-stimulated rat model
H He, Y Zhou, L Liu, J Cui, Y Pei, J Cao, X Hao, L Guo… - Cellular …, 2023 - Elsevier
Silicosis is a progressive and irreversible common occupational disease caused by long-
term inhalation of a large amount of free silica dust. Its pathogenesis is complex, and the …
term inhalation of a large amount of free silica dust. Its pathogenesis is complex, and the …
[HTML][HTML] Emergence of mcr-9.1 in extended-spectrum-β-lactamase-producing clinical Enterobacteriaceae in Pretoria, South Africa: global evolutionary phylogenomics …
JO Sekyere, NE Maningi, L Modipane, NM Mbelle - Msystems, 2020 - ncbi.nlm.nih.gov
ABSTRACT Extended-spectrum--lactamase (ESBL)-producing Enterobacteriaceae are
critical-priority pathogens that cause substantial fatalities. With the emergence of mobile mcr …
critical-priority pathogens that cause substantial fatalities. With the emergence of mobile mcr …
[HTML][HTML] Transmission dynamics of antimicrobial resistance at a national referral hospital in Uganda
Reliable data on antimicrobial resistance (AMR) transmission dynamics in Uganda remains
scarce; hence, we studied this area. Eighty-six index patients and “others” were recruited …
scarce; hence, we studied this area. Eighty-six index patients and “others” were recruited …
Emergence of mcr-9.1 in ESBL-producing Clinical Enterobacteriaceae in Pretoria, South Africa: Global Evolutionary Phylogenomics, Resistome and Mobilome
JO Sekyere, NE Maningi, L Modipane, NM Mbelle - medRxiv, 2019 - medrxiv.org
Background Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae are
critical-priority pathogens that cause substantial fatalities. With the emergence of mobile mcr …
critical-priority pathogens that cause substantial fatalities. With the emergence of mobile mcr …
[HTML][HTML] Synergistic activity between colistin and the ionic liquids 1-methyl-3-dodecylimidazolium bromide, 1-dodecyl-1-methylpyrrolidinium bromide, or 1-dodecyl-1 …
W Florio, C Rizzato, S Becherini, L Guazzelli… - Journal of Global …, 2020 - Elsevier
Objectives Ionic liquids have shown potential for applications as antimicrobials. Their
antimicrobial activity has been shown to be higher against Gram-positive than Gram …
antimicrobial activity has been shown to be higher against Gram-positive than Gram …
[PDF][PDF] Mobile colistin resistance (MCR) Gene, antimicrobial resistance: a global public health threat
T Nusrat, M Haque - Bangladesh Journal of Medical …, 2020 - pdfs.semanticscholar.org
Colistin (Polymyxin E) is a novel antibiotic which gains importance in recent years though it
was discovered a long time ago in 1947 from a bacteria Paenibacillus polymyxa var …
was discovered a long time ago in 1947 from a bacteria Paenibacillus polymyxa var …
[HTML][HTML] Genomic Characterization of Colistin-Resistant Isolates from the King Fahad Medical City, Kingdom of Saudi Arabia
L Okdah, MS AlDosary, A AlMazyed, HM Alkhurayb… - Antibiotics, 2022 - mdpi.com
Background: Whole-genome sequencing is one of the best ways to investigate resistance
mechanisms of clinical isolates as well as to detect and identify circulating multi-drug …
mechanisms of clinical isolates as well as to detect and identify circulating multi-drug …