Progress in cell-based therapies for tendon repair

D Gaspar, K Spanoudes, C Holladay, A Pandit… - Advanced Drug Delivery …, 2015 - Elsevier
The last decade has seen significant developments in cell therapies, based on permanently
differentiated, reprogrammed or engineered stem cells, for tendon injuries and degenerative …

Biophysics and systems biology

D Noble - … Transactions of the Royal Society A …, 2010 - royalsocietypublishing.org
Biophysics at the systems level, as distinct from molecular biophysics, acquired its most
famous paradigm in the work of Hodgkin and Huxley, who integrated their equations for the …

Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

D Kim, CH Kim, JI Moon, YG Chung, MY Chang… - Cell stem cell, 2009 - cell.com
To date, all methods to generate induced pluripotent stem cells (iPSCs) require the use of
genetic materials and/or potentially mutagenic molecules. Here we report the generation of …

Human somatic cell nuclear transfer using adult cells

YG Chung, JH Eum, JE Lee, SH Shim, V Sepilian… - Cell stem cell, 2014 - cell.com
Derivation of patient-specific human pluripotent stem cells via somatic cell nuclear transfer
(SCNT) has the potential for applications in a range of therapeutic contexts. However …

Human oocytes reprogram somatic cells to a pluripotent state

S Noggle, HL Fung, A Gore, H Martinez, KC Satriani… - Nature, 2011 - nature.com
The exchange of the oocyte's genome with the genome of a somatic cell, followed by the
derivation of pluripotent stem cells, could enable the generation of specific cells affected in …

Specific gene-regulation networks during the pre-implantation development of the pig embryo as revealed by deep sequencing

S Cao, J Han, J Wu, Q Li, S Liu, W Zhang, Y Pei… - BMC genomics, 2014 - Springer
Background Because few studies exist to describe the unique molecular network regulation
behind pig pre-implantation embryonic development (PED), genetic engineering in the pig …

[图书][B] Epigenetics: How environment shapes our genes

RC Francis - 2011 - books.google.com
Goodbye, genetic blueprint.... The first book for general readers on the game-changing field
of epigenetics. The burgeoning new science of epigenetics offers a cornucopia of insights …

Transposing bodies of knowledge and technique: Animal models at work in reproductive sciences

C Friese, AE Clarke - Social studies of science, 2012 - journals.sagepub.com
A prominent feature of biological and biomedical research and therapeutics over the past
century is the entanglement of human and other animal bodies in the making and remaking …

Involvement of miRNAs in equine follicle development

SN Schauer, SD Sontakke, ED Watson… - …, 2013 - rep.bioscientifica.com
Protocols for the successful manipulation and preservation of semen in a given species
depend upon a fundamental knowledge of how spermatozoa respond to the …

Development of stem cell-based therapy for Parkinson's disease

F Han, D Baremberg, J Gao, J Duan, X Lu… - Translational …, 2015 - Springer
Parkinson's disease (PD) is one of the most common neurodegenerative disorders of aging,
characterized by the degeneration of dopamine neurons (DA neurons) in the substantial …