WNT signaling is an elaborate and complex collection of signal transduction pathways
mediated by multiple signaling molecules. WNT signaling is critically important for …

Wnt signaling encompasses multiple and complex signaling cascades and is involved in
many developmental processes such as tissue patterning, cell fate specification, and control …

Wnt/β-catenin or canonical Wnt signaling pathway regulates the self-renewal of cancer stem-
like cells (CSCs) and is involved in tumor progression and chemotherapy resistance …

Glioblastoma (GBM) is the most malignant brain tumor and has a dismal prognosis. Aberrant
WNT signaling is known to promote glioma cell growth and dissemination and resistance to …

Background: The Wnt signaling pathway involves secreted glycoproteins that bind to the
Frizzled family receptors to activate intracellular signal transduction events that regulate cell …

Background: The Wnt signaling pathway involves secreted glycoproteins that bind to the
Frizzled family receptors to activate intracellular signal transduction events that regulate cell …

Soft tissue sarcomas (STS) are malignant tumors of mesenchymal origin and represent
around 1% of adult cancers, being a very heterogeneous group of tumors with more than 50 …

Aims Combined magnetic resonance imaging (MRI) of molecular and morpho-functional
changes might prove highly valuable for the elucidation of pathological processes involved …

Wnt signaling pathway plays a critical role in numerous cellular processes, including tumor
initiation, proliferation, invasion/infiltration, metastasis formation and resistance to …

Gliosarcoma (GS) is a rare subtype of glioblastoma (GBM) characterized by both glial and
mesenchymal components. Unlike GBM, there are no specific prognostic markers, and …