Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming
growth factor-β family of ligands. BMPs exhibit widespread utility and pleiotropic, context …

The differentiation of primordial germ cells (PGCs) occurs during early embryonic
development and is critical for the survival and fitness of sexually reproducing species. Here …

With the dramatic development of single-cell RNA sequencing (scRNA-seq) technologies,
the systematic decoding of cell-cell communication has received great research interest. To …

Understanding the molecular pattern of fertility is considered as an important step in
breeding of different species, and despite the high importance of the fertility, little success …

Male-female differences in many developmental mechanisms lead to the formation of two
morphologically and physiologically distinct sexes. Although this is expected for traits with …

Bone morphogenetic proteins (BMPs) are a group of multifunctional growth factors that
belong to the transforming growth factor-β (TGF-β) superfamily of proteins. Originally …

Growth differentiation factor 9 (GDF-9) contributes to early ovarian development and oocyte
survival. Higher concentrations of GDF-9 in follicular fluid (FF) are associated with oocyte …

Elimination of intermuscular bones (IMBs) is vital to the aquaculture industry of cyprinids. In
our previous study, we characterized bmp6 as essential in the development of IMBs in …

Endocrine and paracrine signals can be key regulators of ovarian physiology. The oocyte
secretes growth factors which directly induce follicular development by a complex paracrine …

Colon cancer is a prevalent malignancy affecting the gastrointestinal tract. Oridonin (ORI) is
a promising chemotherapeutic drug used in the treatment of colon cancer. In this study, we …