Ethnobotany and the role of plant natural products in antibiotic drug discovery

G Porras, F Chassagne, JT Lyles, L Marquez… - Chemical …, 2020 - ACS Publications
The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …

A systematic review of plants with antibacterial activities: A taxonomic and phylogenetic perspective

F Chassagne, T Samarakoon, G Porras… - Frontiers in …, 2021 - frontiersin.org
Background: Antimicrobial resistance represents a serious threat to human health across the
globe. The cost of bringing a new antibiotic from discovery to market is high and return on …

Platforms for antibiotic discovery

K Lewis - Nature reviews Drug discovery, 2013 - nature.com
The spread of resistant bacteria, leading to untreatable infections, is a major public health
threat but the pace of antibiotic discovery to combat these pathogens has slowed down …

Plants as sources of new antimicrobials and resistance-modifying agents

AC Abreu, AJ McBain, M Simões - Natural product reports, 2012 - pubs.rsc.org
Covering: up to November 2011 Infections caused by multidrug-resistant bacteria are an
increasing problem due to the emergence and propagation of microbial drug resistance and …

Interaction between phenolics and gut microbiota: role in human health

MV Selma, JC Espin… - Journal of agricultural …, 2009 - ACS Publications
Dietary phenolic compounds are often transformed before absorption. This transformation
modulates their biological activity. Different studies have been carried out to understand gut …

Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study

G Appendino, S Gibbons, A Giana… - Journal of natural …, 2008 - ACS Publications
Marijuana (Cannabis sativa) has long been known to contain antibacterial cannabinoids,
whose potential to address antibiotic resistance has not yet been investigated. All five major …

[HTML][HTML] Antibióticos: importância terapêutica e perspectivas para a descoberta e desenvolvimento de novos agentes

DO Guimarães, LS Momesso, MT Pupo - Química nova, 2010 - SciELO Brasil
There is a continuous need for antibiotics, mainly with new mechanisms of action, since
infectious diseases represent the second major cause of death in the world and bacteria …

Plectranthus: A review of ethnobotanical uses

CW Lukhoba, MSJ Simmonds, AJ Paton - Journal of ethnopharmacology, 2006 - Elsevier
Plectranthus is a large and widespread genus with a diversity of ethnobotanical uses. The
genus is plagued with numerous nomenclatural disharmonies that make it difficult to collate …

Prospects for plant-derived antibacterials

K Lewis, FM Ausubel - Nature biotechnology, 2006 - nature.com
Prospects for plant-derived antibacterials | Nature Biotechnology Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Understanding antimicrobial activities of phytochemicals against multidrug resistant bacteria and biofilms

M Simoes, RN Bennett, EAS Rosa - Natural product reports, 2009 - pubs.rsc.org
Covering: up to November 2008New sources of antimicrobial products need to be identified
due to the existence and constant evolution of resistant microorganisms and phenotypes …