[HTML][HTML] Metabolism and interactions of Ivermectin with human cytochrome P450 enzymes and drug transporters, possible adverse and toxic effects

SP Rendic - Archives of Toxicology, 2021 - Springer
The review presents metabolic properties of Ivermectin (IVM) as substrate and inhibitor of
human P450 (P450, CYP) enzymes and drug transporters. IVM is metabolized, both in vivo …

[HTML][HTML] Safety profile of COVID-19 drugs in a real clinical setting

MN Chiu, M Bhardwaj, SP Sah - European Journal of Clinical …, 2022 - Springer
Purpose The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus has affected millions all over the world and has …

[HTML][HTML] Social media and COVID-19—perceptions and public deceptions of ivermectin, colchicine and hydroxychloroquine: lessons for future pandemics

N Schellack, M Strydom, MS Pepper, CL Herd… - Antibiotics, 2022 - mdpi.com
The capacity for social media to influence the utilization of re-purposed medicines to
manage COVID-19, despite limited availability of safety and efficacy data, is a cause for …

[HTML][HTML] Seguridad y eficacia de ivermectina en tiempos de COVID-19

JC Luque Espino, A Pareja Cruz - Horizonte Médico (Lima), 2021 - scielo.org.pe
Desde su aparición en diciembre de 2019, la infección por SARS-CoV-2 se expandió
rápidamente a todo el mundo. Aproximadamente, el 80% de pacientes con COVID-19 …

Recent strategies for the remediation of Ivermectin from the environment: A critical review

AT Adeleye, KI John, B Helmreich… - Journal of Water Process …, 2023 - Elsevier
Ivermectin (IVM) is arguably one of the most widely consumed drugs due to its wide range of
applications for various diseases such as viruses, cancer, parasites, and inflammation …

[HTML][HTML] Safety and efficacy of ivermectin and doxycycline monotherapy and in combination in the treatment of COVID-19: a scoping review

S Bhowmick, A Dang, BN Vallish, S Dang - Drug safety, 2021 - Springer
Abstract Introduction and Objective Ivermectin (IVM) and doxycycline (DOXY) have
demonstrated in-vitro activity against SARS-CoV-2, and have a reasonable safety profile …

[HTML][HTML] Repurposing Potential of the Antiparasitic Agent Ivermectin for the Treatment and/or Prophylaxis of COVID-19

H Awad, B Hassan, S Dweek, Y Aboelata… - Pharmaceuticals, 2022 - mdpi.com
Due to the rapid, vast, and emerging global spread of the Coronavirus Disease 2019
(COVID-19) pandemic, many drugs were quickly repurposed in a desperate attempt to …

Outcomes of Ivermectin in the treatment of covid-19: a systematic review and meta-analysis

A Castañeda-Sabogal, D Chambergo-Michilot… - medRxiv, 2021 - medrxiv.org
Background To assess the outcomes of ivermectin in ambulatory and hospitalized patients
with COVID-19. Methods Five databases and websites for preprints were searched until …

[HTML][HTML] Computationally repurposed drugs and natural products against RNA dependent RNA polymerase as potential COVID-19 therapies

S Piplani, PK Singh, DA Winkler, N Petrovsky - Molecular biomedicine, 2021 - Springer
Repurposing of existing drugs and drug candidates is an ideal approach to identify new
potential therapies for SARS-CoV-2 that can be tested without delay in human trials of …

Preparation and characterization of inhalable ivermectin powders as a potential COVID-19 therapy

AH Albariqi, WR Ke, D Khanal, S Kalfas… - Journal of aerosol …, 2022 - liebertpub.com
Background: Ivermectin has received worldwide attention as a potential COVID-19 treatment
after showing antiviral activity against SARS-CoV-2 in vitro. However, the pharmacokinetic …