PACSIN proteins in vivo: Roles in development and physiology

V Dumont, S Lehtonen - Acta Physiologica, 2022 - Wiley Online Library
Protein kinase C and casein kinase substrate in neurons (PACSINs), or syndapins (synaptic
dynamin‐associated proteins), are a family of proteins involved in the regulation of cell …

Molecular mechanisms of intercellular dissemination of bacterial pathogens

GC Dowd, R Mortuza, K Ireton - Trends in Microbiology, 2021 - cell.com
Several intracellular bacterial pathogens, including Listeria monocytogenes, Shigella
flexerni, and Rickettsia spp. use an actin-based motility process to spread in mammalian cell …

A patatin-like phospholipase mediates Rickettsia parkeri escape from host membranes

GM Borgo, TP Burke, CJ Tran, NTN Lo… - Nature …, 2022 - nature.com
Rickettsia species of the spotted fever group are arthropod-borne obligate intracellular
bacteria that can cause mild to severe human disease. These bacteria invade host cells …

Manipulation of host cell plasma membranes by intracellular bacterial pathogens

N Kostow, MD Welch - Current opinion in microbiology, 2023 - Elsevier
Highlights•Manipulation of the host cell plasma membrane is critical for infection by
intracellular bacterial pathogens.•Plasma membrane manipulation occurs during bacterial …

Caveolae as potential hijackable gates in cell communication

M Dudãu, E Codrici, C Tanase… - Frontiers in Cell and …, 2020 - frontiersin.org
Caveolae are membrane microdomains described in many cell types involved in
endocytocis, transcytosis, cell signaling, mechanotransduction, and aging. They are found at …

The importance of caveolins and caveolae to dermatology: Lessons from the caves and beyond

AN Egger, A Rajabi‐Estarabadi… - Experimental …, 2020 - Wiley Online Library
Caveolae are flask‐shaped invaginations of the cell membrane rich in cholesterol and
sphingomyelin, with caveolin proteins acting as their primary structural components that …

Impact of Mercaptopurine Metabolites on Disease Outcome in the AIEOP‐BFM ALL 2009 Protocol for Acute Lymphoblastic Leukemia

R Franca, G Stocco, V Kiren, A Tessitore… - Clinical …, 2023 - Wiley Online Library
In the maintenance phase of Associazione Italiana di Ematologia e Oncologia Pediatrica
(AIEOP)‐Berlin‐Frankfurt‐Muenster (BFM) acute lymphoblastic leukemia (ALL) 2009 …

Mechanical forces govern interactions of host cells with intracellular bacterial pathogens

EE Bastounis, P Radhakrishnan, CK Prinz… - Microbiology and …, 2022 - Am Soc Microbiol
To combat infectious diseases, it is important to understand how host cells interact with
bacterial pathogens. Signals conveyed from pathogen to host, and vice versa, may be either …

mDia1 assembles a linear F-actin coat at membrane invaginations to drive Listeria monocytogenes cell-to-cell spreading

AS Dhanda, AW Vogl, F Ness, M Innocenti, JA Guttman - Mbio, 2021 - Am Soc Microbiol
Direct cell-to-cell spreading of Listeria monocytogenes requires the bacteria to induce actin-
based finger-like membrane protrusions in donor host cells that are endocytosed through …

Pushing boundaries: mechanisms enabling bacterial pathogens to spread between cells

JE Raab, DJ Hamilton, TB Harju, TN Huynh… - Infection and …, 2024 - Am Soc Microbiol
For multiple intracellular bacterial pathogens, the ability to spread directly into adjacent
epithelial cells is an essential step for disease in humans. For pathogens such as Shigella …