I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is an important clinical entity diagnosed
by the presence of both subjective and objective evidence of chronic sinonasal …

Objective This update of a 2007 guideline from the American Academy of Otolaryngology—
Head and Neck Surgery Foundation provides evidence-based recommendations to manage …

Objectives Nasal polyps are often characterized by type 2 inflammation and disease
recurrence. We developed a new surgical technique, referred to as reboot approach, which …

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) and type 2 asthma share
the same inflammatory pathophysiology and are frequent comorbidities. Dupilumab, a fully …

Objectives We conducted a systematic literature review (SLR) to determine the
epidemiology and clinical burden of chronic rhinosinusitis with nasal polyps (CRSwNP) and …

Importance Chronic sinusitis is a common inflammatory condition defined by persistent
symptomatic inflammation of the sinonasal cavities lasting longer than 3 months. It accounts …

Endonasal endoscopic sinus surgery is the standard procedure for surgery of most
paranasal sinus diseases. Appropriate frame conditions provided, the respective procedures …

Background: The objective of this study was to investigate the efficacy and safety of early
administration of oral corticosteroids (OC) or nasal corticosteroids (NC) as an add-on to …

Inflammation that is not resolved in due course becomes a chronic disease. The treatment of
chronic inflammatory diseases involves a long-term use of anti-inflammatory drugs such as …