Since the 1980s, we have witnessed the rapid development of genetically modified mouse
models of human diseases. A large number of transgenic and knockout mice have been …

Although it is evident from the literature that altered GABA B receptor function does affect
behavior, these results often do not correspond well. These differences could be due to the …

Targeting receptor proteins, such as ligand-gated ion channels and G protein-coupled
receptors, has directly enabled the discovery of most drugs developed to modulate receptor …

The underlying molecular basis for neurodevelopmental or neuropsychiatric disorders is not
known. In contrast, mechanistic understanding of other brain disorders including …

Our understanding of the molecular determinants of cancer is still inadequate because of
cancer heterogeneity. Here, using epithelial ovarian cancer (EOC) as a model system, we …

Members of the potassium channel tetramerization domain (KCTD) family are soluble non-
channel proteins that commonly function as Cullin3 (Cul3)-dependent E3 ligases. Solution …

The main neurotransmitter in the brain responsible for the inhibition of neuronal activity is γ-
aminobutyric acid (GABA). It plays a crucial role in circuit formation during development …

IntelliCage for mice is a rodent home-cage equipped with four corner structures harboring
symmetrical double panels for operant conditioning at each of the two sides, either by …

Injuries from exposure to explosions rose dramatically during the Iraq and Afghanistan wars,
which motivated investigations of blast-related neurotrauma and operational breaching. In …

Oligodendrocyte gene expression is downregulated in stress‐related neuropsychiatric
disorders, including depression. In mice, chronic social stress (CSS) leads to depression …